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Mittlerweile eine feste Institution und im Terminkalender vieler FM und CREM Verantwortlichen fixiert: Der Münsteraner Facility Management Tag. Seit nunmehr 10 Jahren kommen Interessierte und Freunde der FM-Branche nach Münster, um gemeinsam über Entwicklungen und Trends der Branche zu diskutieren. Der Münsteraner Facility Management Tag verfolgt dabei folgende Schwerpunkte: Darstellung praxisnaher Lösungsansätze Praxisorientierte Wissensvermittlung Stärkung des Transfers zwischen Theorie und Praxis unter dem Motto "Wissenschaft.Praktisch.Machen" Erfahrungsaustausch und best-practice
Mittlerweile eine feste Institution und im Terminkalender vieler FM und CREM Verantwortlichen fixiert: Der Münsteraner Facility Management Tag. Seit nunmehr 10 Jahren kommen Interessierte und Freunde der FM-Branche nach Münster, um gemeinsam über Entwicklungen und Trends der Branche zu diskutieren. Der Münsteraner Facility Management Tag verfolgt dabei folgende Schwerpunkte: Darstellung praxisnaher Lösungsansätze Praxisorientierte Wissensvermittlung Stärkung des Transfers zwischen Theorie und Praxis unter dem Motto "Wissenschaft.Praktisch.Machen" Erfahrungsaustausch und best-practice
Astronomy is driven by the quest for higher sensitivity and improved angular resolution in order to detect fainter or smaller objects. The far-infrared to submillimeter domain is a unique probe of the cold and obscured Universe, harboring for instance the precious signatures of key elements such as water. Space observations are mandatory given the blocking effect of our atmosphere. However the methods we have relied on so far to develop increasingly larger telescopes are now reaching a hard limit, with the JWST illustrating this in more than one way (e.g. it will be launched by one of the most powerful rocket, it requires the largest existing facility on Earth to be qualified). With the Thinned Aperture Light Collector (TALC) project, a concept of a deployable 20 m annular telescope, we propose to break out of this deadlock by developing novel technologies for space telescopes, which are disruptive in three aspects: • An innovative deployable mirror whose topology, based on stacking rather than folding, leads to an optimum ratio of collecting area over volume, and creates a telescope with an eight times larger collecting area and three times higher angular resolution compared to JWST from the same pre-deployed volume; • An ultra-light weight segmented primary mirror, based on electrodeposited Nickel, Composite and Honeycomb stacks, built with a replica process to control costs and mitigate the industrial risks; • An active optics control layer based on piezo-electric layers incorporated into the mirror rear shell allowing control of the shape by internal stress rather than by reaction on a structure. We present in this paper the roadmap we have built to bring these three disruptive technologies to technology readiness level 3. We will achieve this goal through design and realization of representative elements: segments of mirrors for optical quality verification, active optics implemented on representative mirror stacks to characterize the shape correction capabilities, and mechanical models for validation of the deployment concept. Accompanying these developments, a strong system activity will ensure that the ultimate goal of having an integrated system can be met, especially in terms of (a) scalability toward a larger structure, and (b) verification philosophy.
Introduction: Many disease processes are accompanied and promoted
by increased inflammation in the body. Increased concentrations of high-sensitivity C-reactive protein (hs-CRP) in the blood are an indicator of subclinical inflammation, increased disease risk, and an increased risk of early death. A healthy plant-based diet and increased physical activity have been shown to reduce hs-CRP concentrations.
Objectives: Our objective was to test if a healthy lifestyle intervention program can improve hs-CRP levels and other risk factors.
Methodology: We are conducting a non-randomized, controlled intervention study with 6 times of measurement (baseline, after 2.5, 6, 12, 18 and 24 months). Participants in the intervention group (n = 104) took part in a 2.5-month intensive lifestyle program focusing on a plant-based diet (PBD), physical activity, stress management and group support. Currently they are in the less intensive phase (monthly seminars) which will be completed after 24 months. The control group (n = 62) did not take part in any program. In both groups hs-CRP was assessed, and participants with an infection/common cold at any of the times of measurement were excluded from the analyses.
Results: In the intervention group (n = 97) we observed a reduction in hsCRP from baseline to 2.5 months (p < 0.001). In the control group (n = 46) hs-CRP levels increased non-significantly. The changes from baseline to 2.5 months were significantly different between intervention and control (p < 0.01).
Conclusion: Our program led to a clinically relevant reduction in hs-CRP.
Continued follow-up will show if this improvement can be maintained in the intervention group. Our study confirms that a PBD and healthier lifestyle choices can lower hs-CRP.
Quick UDP Internet Connections (QUIC) is a novel transport protocol introducing known features in a new protocol design. To investigate these features and the design, we developed a QUIC implementation in the INET simulation model suite.
In this paper, we describe that implementation, its validation and a result achieved using the simulation model. The result shows the negative impact on throughput, when raising the acknowledgment ratio. We propose a solution and describe how it solves the issue.
Sediment bypass tunnels are an effective and sustainable strategy against reservoir sedimentation. Sediments are diverted into the down-stream during floods without deposition in the reservoir, hence mor-phological and ecological variability increases. One major drawback of these tunnels is the severe invert abrasion due to a combination of high flow velocities and bedload sediment transport. The abrasion phenom-ena is briefly described, different abrasion prediction models are pre-sented and their applicability for the estimation of concrete abrasion is discussed.
A major drawback of sediment bypass tunnels is the potential for severe invert abrasion due to intense bedload sediment transport. This paper briefly describes the abrasion phenomena as well as the available models used to predict invert material loss. The application and calibration is demonstrated on the basis of the Mud Mountain sediment bypass tunnel, Washington, USA.
Adaptive laser resonators with deformable MOEMS mirrors under closed-loop control are discussed and experimental results are presented. The requirements for deformable mirrors and for closed-loop control systems of these mirrors are analyzed. Several deformable mirrors have been characterized and the results are presented. Currently available membrane mirrors deform under laser load and need further development before they can be used for aberration correction of solid state lasers above some tens of Watts. Nevertheless, the results are encouraging and the requirements are within reach of currently available technology. Finally, we demonstrate an Nd.YVO4-laser with a closed-loop adaptive resonator and more than 6 W of output power. The closed-loop system was able to compensate artificially introduced aberrations from a phase plate.