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Oxidative stress plays a critical role in the pathogenesis of chronic diseases. Therefore, improvement of oxidative stress status through lifestyle intervention can play a vital role in preventing and treating chronic diseases. This systematic review aims to provide an overview of articles published in the last decade examining the association between lifestyle intervention and oxidative stress biomarkers in the context of non-communicable diseases. The electronic databases PubMed and Web of Science were searched for relevant studies, following the PRISMA (Preferred Reporting of Systematic Reviews and Meta-Analyses) guidelines. This systematic review focused on the four important oxidative stress biomarkers; glutathione (GSH), superoxide dismutase (SOD), catalase, and malondialdehyde. 671 articles were identified, of which nine met the inclusion criteria. A trend emerged, showing that lifestyle modifications that focus on diet and physical health can improve oxidative stress in the form of an increase in superoxide dismutase and CAT levels and a decrease in Malondialdehyde levels in participants with non-communicable diseases (NCDs), GSH levels were not affected. However, the results are difficult to compare because of the heterogeneity of the methods of the biomarkers studied. Our review indicates that oxidative stress can be influenced by lifestyle modifications and may be an effective tool for the prevention and management of non-communicable diseases. This review also elucidated the importance of analyzing multiple oxidative stress biomarkers to evaluate oxidative stress, it further highlights the need to conduct long-term lifestyle intervention studies on oxidative stress biomarkers to understand the connection between oxidative stress biomarkers, NCDs and Lifestyle intervention.
Hintergrund.ZurQualitätssicherungund
WeiterentwicklungvonBGF-Maßnahmen
(betrieblicheGesundheitsförderung) istes
vonInteresse,einenÜberblicküberwissen
schaftlichuntersuchteBGF-Maßnahmenin
denletztenzweiJahrzehntenzuerlangen.
Zielsetzung.WissenschaftlichevaluierteBGF
MaßnahmenausdenJahren2000–2020wer
denmithilfederinderPraxisdurchdenGKV
SpitzenverbandeingesetztenThemenfelder
aufdiethematischenEntwicklungen,den
Nutzen,aberauchdieSchwächenfürdie
ÜbertragbarkeitindiePraxishinanalysiert.
Methode.EinesystematischeLiteraturrecher
chefürdenPublikationszeitraumzwischen
2000und2020wurdeinzweielektronischen
Datenbankendurchgeführt.
Ergebnisse.DieEinschlusskriterienerfüllten
41Artikel.DiemeistenderindenStudien
durchgeführtenundevaluiertenBGF
MaßnahmenwarenkeineEinzelmaßnahmen,
sondernstelltenProgrammedar. Inihnen
wurdenmehrereThemenfeldergleichzeitig
adressiert.Insgesamtzeigtensichdieinden
StudienuntersuchtenBGF-Maßnahmensehr
heterogen.ZumEndedesUntersuchungszeit
raumesnahmdieAnzahlanPublikationen
zu.
Schlussfolgerung.DieimLeitfadenPräventi
onvorgegebenenBGF-Themenfeldersindbis
aufeinThemenfeldausgewogenvertreten.
DieStudienzudenBGF-Maßnahmen
sindbezogenaufdieVerständlichkeitder
angewendetenDidaktikundMethodikoft
nureingeschränktnachvollziehbarund
somitschwerindieorganisationalePraxis
übertragbar.
Zusammenfassung
Hintergrund. Zur qualitätsbasierten
Weiterentwicklungeffizienter und bedarfs
orientierter Maßnahmen der betrieblichen
Gesundheitsförderung (BGF) ist es von
Interesse, einen Einblick in Ihren Aufbau,
die Ausgestaltung und den Ablauf der
Maßnahmender letztenzwei Jahrzehntezu
erlangen.
Zielsetzung. Auf Basis der arbeitsschutzori
entierten Leitliniendes GKV-Spitzenverbands
wird untersucht, ob vor der Umsetzung
von BGF-Maßnahmen Bedarfserhebungen
mittels Ist-Analysen durchgeführt wurden.
Zusätzlich wird betrachtet,ob die Analysen
„weiche“ Faktoren wie Kultur, Führung und
Beziehungsklima beinhalten. Weiter wird
analysiert, welche wissenschaftlichenTheori
en undModelle denMaßnahmenzugrunde
liegen. Zudem führt die Untersuchungeine
Wirksamkeitsbetrachtungdurch, um zu
ermitteln, welche Effekte die Maßnahmen
erzielten.
Methode. Das vorliegende Literatur-Review
untersucht wissenschaftlichevaluierte BGF
Maßnahmenaus den Jahren 2000–2020.
Hierzu wurde eine systematischeLitera
turrecherche in den zwei elektronischen
DatenbankenScopus und Web of Science
für den benannten Publikationszeitraum
durchgeführt.
Ergebnisse. Die Einschlusskriterienerfüllten
41Artikel.Nur4derStudienführteneine
Ist-Analyse zur Bedarfsbestimmung von
BGF-Maßnahmendurch. 25 Studien führten
Ist-Analysen im Rahmen der Maßnahmen
durch, alle waren arbeitsschutzorientiert.Vier
Studien inkludierten in ihrer Erhebung zu
Beginn Teilaspektevon weichen Faktoren. In
12 Studienwurdenden evaluiertenInterven
tionen unterschiedliche wissenschaftliche
Theorien und Modelle zugrunde gelegt. Alle
Studien berichtetenmindestensfür einzelne
Untersuchungsparametervon positiven
Effekten.
Schlussfolgerung. Vor dem Hintergrund
des Strukturwandels der Wirtschaft und der
beständig zunehmenden Humanisierung
der Arbeit spielen wissenschaftsbasierte
Analyseinstrumentezur Bedarfsbestimmung
eine große Rolle. Zukünftige Analyseinstru
mentesolltenvon derWissenschaftkonzipiert
und erprobt werden und zusätzlich zur
Arbeitsschutzorientierung die immateriellen,
weichen Faktoren Kultur, Führung und
Beziehungsklima beinhalten. Trotz der
Empfehlungen, Maßnahmenauf Grundlage
von Theorien und Modellen zu konzipieren,
wurde dieses Potenzial von nur wenigen
wissenschaftlichevaluiertenStudien genutzt.
Die Wirksamkeitsbetrachtungzeigt, dass alle
Studien mindestensfür Teile Ihrer Evaluation
von positiven Effekten berichten. Dieses
Untersuchungsergebnisdes Reviewsweist auf
ein Publikationsbiashin
Background: Establishing a healthy lifestyle has a great potential to reduce the prevalence of non-communicable diseases (NCDs) and their risk factors. NCDs contribute immensely to the economic costs of the health care system arising from therapy, medication use, and productivity loss.
Aim: The aim of this study was to evaluate the effect of the Healthy Lifestyle Community Program (cohort 2; HLCP-2) on medication use and consequently on medication costs for selected NCDs (diabetes, hypertension, and dyslipidemia).
Methods: Data stem from a 24-month non-randomised, controlled intervention trial aiming to improve risk factors for NCDs. Participants completed questionnaires at six measurement time points assessing medication use, from which costs were calculated. The following medication groups were included in the analysis as NCD medication: glucose-lowering medications (GLM), antihypertensive drugs (AHD) and lipid-lowering drugs (LLD). Statistical tests for inter- and intra-group comparison and multiple regression analysis were performed.
Results: In total, 118 participants (intervention group [IG]: n = 79; control group [CG]: n = 39) were considered. Compared to baseline medication use decreased slightly in the IG and increased in the CG. Costs for NCD medication were significantly lower in the IG than in the CG after 6 (p = 0.004), 12 (p = 0.040), 18 (p = 0.003) and 24 months (p = 0.008). After multiple regression analysis and adjusting for confounders, change of costs differed significantly between the groups in all final models.
Conclusion: The HLCP-2 was able to moderately prevent an increase of medication use and thus reduce costs for medication to treat NCDs with the greatest impact on AHD.
Non-communicable diseases (NCD) are associated with high costs for healthcare systems. We evaluated changes in total costs, comprising direct and indirect costs, due to a 24-month non-randomized, controlled lifestyle intervention trial with six measurement time points aiming to improve the risk profile for NCDs. Overall, 187 individuals from the general population aged ≥18 years were assigned to either the intervention group (IG; n = 112), receiving a 10-week intensive lifestyle intervention focusing on a healthy, plant-based diet; physical activity; stress management; and community support, followed by a 22-month follow-up phase including monthly seminars, or a control group (CG; n = 75) without intervention. The complete data sets of 118 participants (IG: n = 79; CG: n = 39) were analyzed. At baseline, total costs per person amounted to 67.80 ± 69.17 EUR in the IG and 48.73 ± 54.41 EUR in the CG per week. The reduction in total costs was significantly greater in the IG compared to the CG after 10 weeks (p = 0.012) and 6 months (p = 0.004), whereas direct costs differed significantly after 10 weeks (p = 0.017), 6 months (p = 0.041) and 12 months (p = 0.012) between the groups. The HLCP-2 was able to reduce health-related economic costs, primarily due to the reduction in direct costs.
Organic food quality is based on processing. While the EU organic production regulation focuses on agricultural production, private standards provide more detailed information about further processing. For the development of organic processing, practitioner perspectives can provide valuable input. To get insight into practitioner perspectives, we conducted semi-structured expert interviews with nine employees of seven partly organic juice processing companies from Germany and Austria. Interview topics were (i) quality of organic juice processing in general, (ii) assessment of specific processing techniques, (iii) product quality of organic juice and (iv) flow of information between producer and consumer. We conducted a thematic analysis. We found that the experts’ understanding of process quality mostly includes more aspects than the EU organic production regulation. It covers the whole food chain plus aspects of social and environmental sustainability. The experts prefer directly bottled juice of local raw materials but chiefly accept juice made from concentrate of exotic raw materials because of environmental concerns. Organic juice is preferred when it is cloudy and natural fluctuations are interpreted as an indicator of natural quality. The experts report that consumer information is challenging because of low food literacy. Raising this might help reduce the number of processed juices on the market.
Purpose: Organic food processing must include organic principles to be authentic. This qualitative study aims to understand the processors' understanding of organic food processing quality.
Design/methodology/approach: This study is based on semi-structured expert interviews with eight employees of six purely or partly organic dairies from Germany and Switzerland. Interview themes are (1) quality of organic milk processing in general, (2) assessment of specific processing techniques, (3) product quality of organic milk and (4) flow of information between producer and consumer. The interviews have been audio-recorded, transcribed verbatim and thematically analysed.
Findings: (1) Experts prefer minimal processing; some prefer artisanal processing, whilst others stress the advantages of mechanisation. (2) High temperature short time (HTST) pasteurisation and mechanical processing techniques are accepted; ultra-high-temperature (UHT) milk processing is partly rejected. (3) Traditional taste and valuable ingredients should be present in the final product. Natural variances are judged positively. (4) Consumers' low level of food technology literacy is challenging for communication.
Research limitations/implications: The results cannot be generalised due to the qualitative study design. Further studies, e.g. qualitative case analyses and studies with a quantitative design, are necessary to deepen the results.
Practical implications: The paper shows which processing technologies experts consider suitable or unsuitable for organic milk. The paper also identifies opportunities to bridge the perceived gap between processors' and consumers' demands.
Originality/value: The study shows the challenges of processors in expressing the processors' understanding of process quality.
The concern for the environment among European consumers is growing and in the future the need for sustainable shopping is expected to increase. Through transparent on-packaging communication with consumers, organic producers have the opportunity to show attributes of organic production system and build a strong market position. The aim of the study was to analyse voluntary packaging information on organic milk from four European markets in the context of organic food quality, i.e., Germany, the Netherlands, Italy and Poland. More specifically, the textual content of 106 organic milk packages was analysed and voluntary information on each package was categorized according to process- and product-related organic milk attributes. The assortment and content of voluntary packaging information varied across the four countries. The largest number of products was found on the German market (37) and the smallest on the Polish market (14). Dutch milk had the greatest amount of voluntary information on animal welfare, product locality, environmental protection, quality confirmation, naturalness and nutritional value. German milk had the most information on enjoyment and conditions of processing, while the Italian milk on the social perspective. The products available on the Polish market had the least voluntary information. Pasteurized organic milk had noticeably more information about organic quality attributes than micro filtrated and UHT milk.
Who cares (for whom)
(2022)
Introduction: Moving towards a more plant-based dietary pattern would likely be beneficial in terms of a variety of sustainability dimensions.
Methodology: We conducted a 2-year intervention study with six measurement time points (baseline, 10 weeks, 6 months, 1 year, 1½ years, 2 years) in rural northwest Germany. The intervention consisted of a lifestyle programme, and dietary recommendations were to move towards a healthy, plant-based diet. The control group received no intervention. Diet quality was assessed with the healthful plant-based diet index (hPDI).
Results: In the intervention group (n = 67), the 2-year trajectory of hPDI was significantly higher compared to control (n = 39; p 0.001; between-group difference: 5.7 (95% CI 4.0, 7.3) food portions/day; adjusted for baseline). The 2-year trajectory of meat intake was significantly lower in the intervention group (n = 79) compared to control (n = 40; p 0.001; between-group difference: -0.7 (95% CI -0.9, -0.5) portions/day; adjusted for baseline).
Conclusion: Our study confirms that plant-based nutrition education in the general population is likely to result in at least modest dietary improvements in terms of general healthfulness and meat reduction.
Introduction: Many disease processes are accompanied and promoted
by increased inflammation in the body. Increased concentrations of high-sensitivity C-reactive protein (hs-CRP) in the blood are an indicator of subclinical inflammation, increased disease risk, and an increased risk of early death. A healthy plant-based diet and increased physical activity have been shown to reduce hs-CRP concentrations.
Objectives: Our objective was to test if a healthy lifestyle intervention program can improve hs-CRP levels and other risk factors.
Methodology: We are conducting a non-randomized, controlled intervention study with 6 times of measurement (baseline, after 2.5, 6, 12, 18 and 24 months). Participants in the intervention group (n = 104) took part in a 2.5-month intensive lifestyle program focusing on a plant-based diet (PBD), physical activity, stress management and group support. Currently they are in the less intensive phase (monthly seminars) which will be completed after 24 months. The control group (n = 62) did not take part in any program. In both groups hs-CRP was assessed, and participants with an infection/common cold at any of the times of measurement were excluded from the analyses.
Results: In the intervention group (n = 97) we observed a reduction in hsCRP from baseline to 2.5 months (p < 0.001). In the control group (n = 46) hs-CRP levels increased non-significantly. The changes from baseline to 2.5 months were significantly different between intervention and control (p < 0.01).
Conclusion: Our program led to a clinically relevant reduction in hs-CRP.
Continued follow-up will show if this improvement can be maintained in the intervention group. Our study confirms that a PBD and healthier lifestyle choices can lower hs-CRP.
Coworking Spaces sind mittlerweile fester Bestandteil der digitalen Arbeitslandschaft in Großstädten. Nach und nach halten sie auch im ländlichen Raum Einzug. Studien und Modellprojekte haben bewiesen, dass sie sowohl gesellschaftlich als auch wirtschaftlich eine positive Wirkung auf strukturschwächere Regionen haben können. Sie bieten ein attraktives Umfeld für Kreative und Gründer und ermöglichen den Austausch mit lokalen Unternehmen. Außerdem können sie dafür sorgen, dass Pendler* innen zum Arbeiten vor Ort bleiben.
In weniger dicht besiedelten Regionen, wie dem Münsterland, ist der profitable Betrieb von Coworking Spaces bisweilen schwierig. Da naturgemäß die Standortwahl eines Coworking Space ein entscheidendes Kriterium für seine spätere Wirtschaftlichkeit ist, wird diese in der vorliegenden Studie untersucht. Dazu werden auf Coworking Spaces zugeschnittene und von Experten gewichtete Standortfaktoren aufgestellt und die 65 Orte des Münsterlands anhand dieser Faktoren bewertet. So entsteht ein Ranking, welches aufzeigt, wo die besten Voraussetzungen für Coworking Spaces herrschen.
In einigen Städten im Münsterland gibt es bereits Coworking Spaces. Einem Großteil dieser Orte wird durch diese Studie eine gute Eignung bestätigt. Beispielsweise schneiden Rheine und Bocholt aufgrund ihrer hohen Einwohnerzahl am besten ab. Es wird jedoch deutlich, dass auch andere Faktoren ausschlaggebend sein können. So bewerten Expert*innen die digitale Infrastruktur und Erreichbarkeit als sehr wichtig. Für diese Faktoren stellen vergleichsweise kleine Orte die Bestwerte, die bislang noch keine Coworking Spaces vorweisen können.
Die Ergebnisse informieren Betreiber*innen von Coworking Spaces und solche, die es werden wollen, sowie politische Entscheidungsträger*innen über mögliche Potenziale in den jeweiligen Orten. Sie zeigen auf, an welchen Stellschrauben gedreht werden kann, um gute Voraussetzungen zu schaffen. Darüber hinaus wird empfohlen, das entstehende Angebot aufeinander abzustimmen und gemeinschaftlich vorzugehen – so, wie es der Begriff Coworking bereits verdeutlicht.
Background. Ketone bodies are a highly relevant topic in nutrition and medicine. -e influence of medium-chain triglycerides (MCT) on ketogenesis is well known and has been successfully used in ketogenic diets for many years. Nevertheless, the effects of MCTs and coconut oil on the production of ketone bodies have only partially been investigated. Furthermore, the increased mobilisation of free fatty acids and release of catabolic hormones by caffeine suggest an influence of caffeine on ketogenesis.
Methods. In a controlled, double-blind intervention study, seven young healthy subjects received 10mL of tricaprylin (C8), tricaprin (C10), C8/C10 (50% C8, 50% C10), or coconut oil with or without 150 mg of caffeine, in 250mL of decaffeinated coffee, over ten interventions. At baseline and after every 40 minutes, for 4 h, ßHB and glucose in capillary blood as well as caffeine in saliva were measured. Furthermore, questionnaires were used to survey sensory properties, side effects, and awareness of hunger and satiety. Results. -e interventions with caffeine caused an increase in ßHB levels—in particular, the interventions with C8 highly impacted ketogenesis. -e effect decreased with increased chain lengths. All interventions showed a continuous increase in hunger and diminishing satiety. Mild side effects (total � 12) occurred during the interventions. Conclusions. -e present study demonstrated an influence of caffeine and MCTon ketogenesis. -eaddition of caffeine showed an additive effect on the ketogenic potential of MCT and coconut oil. C8 showed the highest ketogenicity.
Food-processing companies are controlled by societal influences and economic interests, but their efforts with regard to reducing food loss and waste are very different. This qualitative study aims to identify basic recommendations of good practice for the food-processing industry in order to prevent and handle food loss and waste. For this purpose, a comprehensive literature review was conducted in the field of food waste prevention and data was collected from thirteen German companies. The findings summarize the recommendations of good practice, which cover the entire supply chain from supplier to consumer and beyond. The analysis showed that the participating companies are already partially aware of operational measures, even if they are applied or mentioned without a systematic approach. Furthermore, the analysis revealed that most activities relate to internal matters, like processing, employees and utilization. However, the responsibility of foodprocessing companies does not end with internal processes to reduce food waste. The results show that some companies are already aware of their responsibility to be involved along the entire supply chain. Finally, the results show that the needs of consumers and suppliers must also be considered in order to reduce food waste, in addition to direct reduction measures. This paper highlights nine important stages and 53 basic recommendations for companies to address food loss and waste in order to improve their practices.