TY - CHAP A1 - Köder, Christian A1 - Englert, Heike ED - Serra Majem, Lluis ED - Luz Fernández, María T1 - Influence of a Community-Based Lifestyle Intervention Program Including Recommendations for a Plant-Based Diet on Cardiovascular Risk Parameters T2 - Nutrients 2019: Nutritional Advances in the Prevention and Management of Chronic Disease N2 - Background: Cardiovascular disease (CVD) is the leading cause of death in industrialized countries and worldwide. The concentrations of serum total and LDL cholesterol as well as a higher intima media thickness of the common carotid artery (ccIMT) are associated with higher CVD risk. Measuring ccIMT makes it possible to already assess the atherosclerotic process at the subclinical stage. Methods: A two-year nonrandomized, controlled intervention study with 6 times of measurement (baseline; at 10 weeks; at 6, 12, 18, and 24 months). Participants of the intervention group (n = 112) took part in a ten-week intensive lifestyle program (including bi-weekly group sessions, workshops, and personal health coaching at baseline and at 10 weeks), followed by a less intensive phase (monthly lifestyle education group sessions). The control group (n = 87) did not take part in any program. In both groups, CVD-related parameters were assessed, including cholesterol (total, LDL, HDL), ccIMT (not assessed at 10 weeks), as well as health behavior (questionnaires). In between group means were compared with ANOVA using IBM SPSS 24. Results: After 10 weeks, the intervention group showed a reduction in total, LDL, and HDL cholesterol values compared to baseline (p < 0.01). In the control group, these parameters did not change. After 6 months, there was no statistically significant difference in ccIMT change between intervention and control. The 6-month blood results are not available yet. Conclusion: Our lifestyle program led to clinically relevant reductions in total and LDL cholesterol. Continued follow-up will show whether the improvement of cholesterol levels will be maintained in the intervention group and whether ccIMT will differ between intervention and control. KW - cholesterol, lifestyle medicine, intima media thickness, cardiovascular disease, atherosclerosis Y1 - 2019 UR - https://nutrients2019.sciforum.net/conferences_files/225/customs/e28f76e450e4716fccaa958564f81120.pdf SP - 185 EP - 185 PB - MDPI Nutrients 2019 Conference CY - Barcelona, Spain ER - TY - CHAP A1 - Husain, Sarah A1 - Anand, Corinna A1 - Musiol, Jennifer A1 - Bordewick-Dell, Ursula A1 - Englert, Heike ED - Majem, Lluis Serra ED - Fernández, María Luz T1 - Effect of a Community-Based Lifestyle Intervention Program on the Blood Plasma Levels of Lipid Peroxidation in a Rural German Population after 10 Weeks of Intensive Intervention T2 - Nutrients 2019: Nutritional Advances in the Prevention and Management of Chronic Disease N2 - Lifestyle diseases are linked with hyper-reactivity of inflammatory and immune cells. These cells generate free radicals in the patients, which results in oxidative stress. Recent studies have brought attention to the role of oxidative stress, defined as an imbalance between reactive oxygen species (ROS) and antioxidants. Our research was focused on studying the effects of a community-based lifestyle intervention program on oxidative stress paraments in the plasma of a rural German community. In our study, we examined 105 participants in the intervention group and 70 participants in the control group. The intervention group received 10 weeks of intensive intervention in the form of seminars and workshops. The plasma levels were analyzed at baseline and after 10 weeks of intervention. This is a first-of-itskind study which elucidates the impact of an intensive lifestyle intervention program on the oxidative stress markers in German rural participants. The primary focus of our study was to motivate and encourage participants to switch over toward a healthier lifestyle by improving their knowledge and making them more aware of the principles of healthy living. This may be a useful community program approach, modifiable for different communities by health-services planners in the coming future. KW - Oxidative stress, anti-oxidants,free radicals, lipid peroxidation, nutrition, lifestyle,health,intervention,community Y1 - 2019 UR - https://nutrients2019.sciforum.net/#custom889 SP - 219 EP - 219 PB - MDPI Nutrients 2019 Conference CY - Barcelona, Spain ER -