TY  - JOUR
A1  - Koeder, Christian
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - Is fruit intake associated with common carotid intima-media thickness?
JF  - European Journal of Public Health
N2  - Background
Common carotid intima-media thickness (ccIMT) is an established risk marker for cardiovascular events, including myocardial infarction and stroke, which are of high public health relevance. While a higher fruit intake is generally considered beneficial for cardiovascular health, recent studies have shown that a fruit intake of > 2 portions per day may be harmful. Therefore, we tested if there is an association between categories of fruit intake and mean ccIMT.

Methods
We conducted an exploratory, non-prespecified, cross-sectional analysis of baseline values of 167 mostly middle-aged participants of a controlled lifestyle intervention, recruited from the general population in rural northwest Germany (male: n = 58; female: n = 109). Fruit intake was classified into low (<1 portion of fruit/day), intermediate (1-2 portions of fruit/day), and high (>2 portions of fruit/day). Mean ccIMT was measured in accordance with the Mannheim consensus. Between-group differences in mean ccIMT were assessed with analysis of covariance.

Results
Mean age was 57.3 ± 0.7 years (mean ± SEM). Mean fruit intake was 1.6 ± 0.1 portions/day. Average mean ccIMT was 0.679 ± 0.010 mm. There was a significant difference in mean ccIMT between subjects with low (0.676 ± 0.020 mm; n = 50), intermediate (0.653 ± 0.014 mm; n = 72), and high fruit intake (0.724 ± 0.019 mm; n = 45; p = 0.016). But this difference was attenuated when adjusting for age, sex, and homocysteine (p = 0.418).

Conclusions
We found only a non-significant association between consuming >2 portions of fruit per day and ccIMT. Thus, our study could not confirm a negative effect of fruit intake on ccIMT. Age, sex, and homocysteine may confound this association.

Key messages
Current recommendations of 2 portions of fruit per day seem adequate and do not negatively influence carotid intima-media thickness.

Future studies should address confounding of the association between fruit intake and cardiovascular risk markers.
KW  - plant-based diet
KW  - carotid intima-media thickness
KW  - fruit
Y1  - 2021
U6  - http://dx.doi.org/10.1093/eurpub/ckab165.391
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Wegscheider, K.
A1  - Berger, H.
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Windler, E.
A1  - Katus, H.
A1  - Willich, S.
T1  - Is patient self-report an adequate tool for monitoring cardiovascular conditions in patients with hypercholesterolemia? – Results of the ORBITAL Study
JF  - J Public Health (Oxf)
Y1  - 2010
SN  - 1741-3850
VL  - 32
IS  - 3
SP  - 387
EP  - 394
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Wegscheider, K.
A1  - Berger, H.
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Reinhold, T.
A1  - Windler, E.
A1  - Katus, HA.
A1  - Willich, SN.
T1  - Productivity loss as a major component of disease-related costs in patients with hypercholesterolemia in Germany
JF  - Clin Res Cardiol
Y1  - 2008
SN  - 1861-0692
VL  - 97
SP  - 152-9
EP  - -
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - Effect of a 6-Month Controlled Lifestyle Intervention on Common Carotid Intima-Media Thickness
JF  - The journal of nutrition, health & aging
KW  - plant-based diet
KW  - cardiovascular disease
KW  - kardiovaskuläre Erkrankungen
KW  - Prävention
Y1  - 2021
U6  - http://dx.doi.org/10.1007/s12603-021-1628-0
ER  - 
TY  - JOUR
A1  - Koeder, Christian
T1  - Understanding the situation of vegans
JF  - Eating and Weight Disorders
KW  - vegan
KW  - plant-based diet
KW  - orthorexia nervosa
Y1  - 2021
U6  - http://dx.doi.org/10.1007/s40519-021-01127-2
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Husain, Sarah
A1  - Kranz, Ragna-Marie
A1  - Anand, Corinna
A1  - Alzughayyar, Dima
A1  - Schoch, Nora
A1  - Hahn, Andrea
A1  - Englert, Heike
T1  - Healthy lifestyle changes favourably affect common carotid intima-media thickness: the Healthy Lifestyle Community Programme (cohort 2)
JF  - Journal of Nutritional Science
N2  - Common carotid intima-media thickness (ccIMT) progression is a risk marker for cardiovascular disease (CVD), whereas healthy lifestyle habits are associated with lower ccIMT. The objective of the present study was to test whether a healthy lifestyle intervention can beneficially affect ccIMT progression. A community-based non-randomised, controlled lifestyle intervention was conducted, focusing on a predominantly plant-based diet (strongest emphasis), physical activity, stress management and social health. Assessments of ccIMT were made at baseline, 6 months and 1 year. Participants had an average age of 57 years and were recruited from the general population in rural northwest Germany (intervention: n 114; control: n 87). From baseline to 1 year, mean ccIMT significantly increased in both the intervention (0⋅026 [95 % CI 0⋅012, 0⋅039] mm) and control group (0⋅045 [95 % CI 0⋅033, 0⋅056] mm). The 1-year trajectory of mean ccIMT was lower in the intervention group (P = 0⋅022; adjusted for baseline). In a subgroup analysis with participants with high baseline mean ccIMT (≥0⋅800 mm), mean ccIMT non-significantly decreased in the intervention group (−0⋅016 [95 % CI −0⋅050, 0⋅017] mm; n 18) and significantly increased in the control group (0⋅065 [95 % CI 0⋅033, 0⋅096] mm; n 12). In the subgroup, the 1-year trajectory of mean ccIMT was significantly lower in the intervention group (between-group difference: −0⋅051 [95 % CI −0⋅075, −0⋅027] mm; P < 0⋅001; adjusted for baseline). The results indicate that healthy lifestyle changes may beneficially affect ccIMT within 1 year, particularly if baseline ccIMT is high.
KW  - plant-based diet
KW  - carotid intima-media thickness
KW  - cardiovascular disease
KW  - atherosclerosis
KW  - lifestyle
Y1  - 2022
UR  - https://www.cambridge.org/core/journals/journal-of-nutritional-science/article/healthy-lifestyle-changes-favourably-affect-common-carotid-intimamedia-thickness-the-healthy-lifestyle-community-programme-cohort-2/DD29870A14031B1EB3DF112B2A381695#article
U6  - http://dx.doi.org/10.1017/jns.2022.46
VL  - 11
ER  - 
TY  - JOUR
A1  - Willich, S. N.
A1  - Englert, Heike
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Wegscheider, K.
A1  - Windler, E.
A1  - Katus, H. A.
A1  - Müller-Nordhorn, J.
T1  - Impact of a compliance program on cholesterol control: results of the randomized ORBITAL study in 8108 patients treated with rosuvastatin
JF  - Eur J Cardiovasc Prev Rehabil
N2  - Abstract This study extends previous research evaluating the association between the CHIP intervention, change in body weight, and change in psychological health. A randomized controlled health intervention study lasting 4 wk. was used with 348 participants from metropolitan Rockford, Illinois; ages ranged from 24 to 81 yr. Participants were assessed at baseline, 6 wk., and 6 mo. The Beck Depression Inventory (BDI) and three selected psychosocial measures from the SF-36 Health Survey were used. Significantly greater decreases in Body Mass Index (BMI) occurred after 6 wk. and 6 mo. follow-up for the intervention group compared with the control group, with greater decreases for participants in the overweight and obese categories. Significantly greater improvements were observed in BDI scores, role-emotional and social functioning, and mental health throughout follow-up for the intervention group. The greater the decrease in BMI through 6 wk., the better the chance of improved BDI score, role-emotional score, social functioning score, and mental health score, with odds ratios of 1.3 to 1.9. Similar results occurred through 6 mo., except the mental health variable became nonsignificant. These results indicate that the CHIP intervention significantly improved psychological health for at least six months afterwards, in part through its influence on lowering BMI.
Y1  - 2009
VL  - 16
SP  - 180
EP  - 187
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Kranz, Ragna-Marie
A1  - Anand, Corinna
A1  - Husain, Sarah
A1  - Alzughayyar, Dima
A1  - Schoch, Nora
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - Effect of a 1-year controlled lifestyle intervention on body weight and other risk markers (the Healthy Lifestyle Community Programme, cohort 2)
JF  - Obesity Facts
KW  - Adipositas
KW  - Lebensstil
KW  - pflanzenbasierte Ernährung
Y1  - 2021
U6  - http://dx.doi.org/10.1159/000521164
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Wegscheider, K.
A1  - Berger, H.
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Reinhold, T.
A1  - Windler, E.
A1  - Katus, HA.
A1  - Willich, SN.
T1  - Effect of an adherence-enhancing program on health-related quality of life in patients with hypercholesterolemia
JF  - Eur J Integrative Med
Y1  - 2008
SN  - 1876-3820
VL  - 1
IS  - 1
SP  - 24
EP  - -
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Windler, E.
A1  - Meyer-Sabellek, W.
A1  - Katus, H.
A1  - Wegscheider, K.
A1  - Willich, SN.
T1  - Disease-related costs in patients with hypercholesterolemia
JF  - J Epi Community Health
Y1  - 2004
SN  - 0143-005X
VL  - 58 (Suppl.)
SP  - 20
EP  - -
ER  -