TY  - JOUR
A1  - Ngo-Matip, M. E.
A1  - Constant Anatole, P
A1  - Azabji-K, Marcel AKN
A1  - Colizzi, Vittorio
A1  - Temgoua, E
A1  - Nkenfack, G
A1  - Englert, Heike
A1  - Nya, PC
A1  - Moukette, M B
A1  - Fosso, PE
A1  - Stefanini, Philippe
A1  - Ngogang, Y J
A1  - Mbofung, C. Moise
T1  - Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naive patients in Yaounde - Cameroon: a randomized trial study
JF  - Lipids in Health and Disease
Y1  - 2014
U6  - http://dx.doi.org/10.1186/1476-511x-13-191
VL  - 13
IS  - 191
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J
A1  - Muckelbauer, R
A1  - Englert, Heike
A1  - Grittner, U
A1  - Berger, H
A1  - Sonntag, F
A1  - Völler, H
A1  - Wegscheider, K
A1  - Katus, H
A1  - Willich, S
T1  - Longitudinal association between body mass index and health-related quality of life
JF  - PLoS One
Y1  - 2014
VL  - 9
IS  - 3
SP  - 1
EP  - 10
ER  - 
TY  - JOUR
A1  - Nkengfack, G
A1  - Torimiro, J
A1  - Ngogang, J
A1  - Englert, Heike
T1  - Effects of nutritional education and lifestyle modification on the nutritional status of HIV positive patients: results of a cluster randomized intervention over a period of six months
JF  - Global Epidemic Obesity
Y1  - 2013
VL  - 5
IS  - 1
SP  - 1
EP  - 8
ER  - 
TY  - JOUR
A1  - Nkengfak, G
A1  - Turimiro, J
A1  - Nkongang, N
A1  - Englert, Heike
T1  - A review of nutrition in Cameroon: Food supply, factors influencing nutritional habit and impact on micronutrient (Vitamin A, Iodine, Iron) status
JF  - The Journal of Medicine and Health Sciences
Y1  - 2011
VL  - 12
IS  - 1
ER  - 
TY  - JOUR
A1  - Nkengfack, G
A1  - Torimiro, J
A1  - Ngogang, J
A1  - Binting, S
A1  - Roll, S
A1  - Tinnemann, P
A1  - Englert, Heike
T1  - Effects of an HIV-Care-Program on immunological parameters in HIV-positive patients in Yaoundé, Cameroon: a cluster-randomized trial
JF  - Int J Public Health
Y1  - 2014
U6  - http://dx.doi.org/10.1007/s00038-014-0547-9
VL  - 59
SP  - 509
EP  - 517
ER  - 
TY  - JOUR
A1  - Nkengfack, G
A1  - Ngogang, J
A1  - Englert, Heike
T1  - Effects of "5 a day" fruit and vegetable intake on micronutrient level and oxidative stress markers in HIV positive patients in Yaoundé, Cameroon: A cluster randomized trial
JF  - Oxid Antioxid Med Sci
Y1  - 2013
VL  - 2
IS  - 4
SP  - 275
EP  - 284
ER  - 
TY  - JOUR
A1  - Wennehorst, K
A1  - Diehl, H
A1  - Mildenstein, K
A1  - Saliger, B
A1  - Tigges, C
A1  - Keil, T
A1  - Englert, Heike
T1  - A Comprehensive Lifestyle Intervention to Prevent Type 2 Diabetes and Cardiovascular Diseases: The CHIP Germany Trial
JF  - Prevention Sciences
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s11121-015-0623-2
VL  - 17
SP  - 386
EP  - 397
ER  - 
TY  - CHAP
A1  - Englert, Heike
T1  - Antioxidants and HIV/AIDS
T2  - Zampelas A, Micha E (Hg.), Antioxidants in Health and Disease
Y1  - 2015
SN  - 978-1-4665-8003-9
SP  - 263
EP  - 278
PB  - Taylor & Francis Catalog
ER  - 
TY  - JOUR
A1  - Muckelbauer, Rebecca
A1  - Englert, Heike
A1  - Rieckmann, Nina
A1  - Chen, Chih-Mei
A1  - Wegscheider, Karl
A1  - Völler, Heinz
A1  - Hugo, A.
A1  - Katus, Stefan
A1  - Willich, N.
A1  - Müller-Nordhorn, Jacqueline
T1  - Long-term effect of a low-intensity smoking intervention embedded in an adherence program for patients with hypercholesterolemia: Randomized controlled trial
JF  - Preventive Medicine
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.ypmed.2015.05.026
VL  - 77
SP  - 155
EP  - 161
ER  - 
TY  - JOUR
A1  - Muckelbauer, R
A1  - CM, Hettler-Chen
A1  - Englert, Heike
A1  - Wegscheider, K
A1  - Völler, H
A1  - Katus, H
A1  - Willich, S
A1  - Müller-Nordhorn, J
T1  - Type of association between body mass index and health-related quality of life differs by smoking status in high-risk cardiovascular patients
JF  - Eur J Epidemiol
Y1  - 2015
VL  - Supplement
ER  - 
TY  - CHAP
A1  - Englert, Heike
T1  - Effect of an HIV-care-program on immunological parameters in HIV-positive patients in Yaounde, Cameroon: A cluster randomized trial.
T2  - Health Care: Current Reviews; OMICS International Conferences
Y1  - 2015
SN  - 2375-4273
U6  - http://dx.doi.org/10.4172/2375-4273.C1.008
PB  - HCCR (open access journal)
CY  - New Delhi, India
ET  - 3
ER  - 
TY  - CHAP
A1  - Tigges, C
A1  - Englert, Heike
T1  - Impact of a Lifestyle Coaching Intervention on Nutritional Behavior and Physical Behavior Change in Prevention of Type 2 Diabetes and Importance of Social-Cognitive Variables
T2  - Health Care: Current Reviews
Y1  - 2015
SN  - 2375-4273
U6  - http://dx.doi.org/10.4172/2375-4273.C1.008
PB  - HCCR (open access journal)
CY  - New Delhi, India
ET  - 3
ER  - 
TY  - CHAP
A1  - Englert, Heike
A1  - Nkengfack, Germaine
T1  - Antioxidants in HIV patients in Africa: supplements, local diet and education
T2  - Victor Preedy, HIV/AIDS: Oxidative Stress and Dietary Antioxidants
Y1  - 2016
SP  - 1
EP  - 33
PB  - King´s College London
CY  - London
ET  - 1. Auflage
ER  - 
TY  - JOUR
A1  - Wennehorst, K
A1  - Mildenstein, K
A1  - Saliger, B
A1  - Keil, T
A1  - Englert, Heike
T1  - Does a holistic lifestyle intervention program improve health-related quality of life and psychological wellbeing in adults and diabetes risk?
JF  - Diabetes Managment
Y1  - 2017
SN  - 1758-1907
VL  - 7
IS  - 3
SP  - 256
EP  - 263
ER  - 
TY  - CHAP
A1  - Koeder, Christian
A1  - Englert, Heike
T1  - Nutrient recommendations for vegans – what should we recommend?
T2  - Kessler, C.: Complementary Medicine Research, Vol. 25, Suppl. 1
Y1  - 2018
U6  - http://dx.doi.org/10.1159/000488417
PB  - S. Karger
CY  - Basel
ER  - 
TY  - CHAP
A1  - Englert, Heike
A1  - Brune, M
A1  - Kraatz, A
T1  - The effects of a functional food, high in mono-, di-, oligo- and polysaccharids, on the blood sugar level in type 1 diabetics during a 10 km run
T2  - Martirosyan D & Nishizawa M: Encounters of Functional Foods and Asian Traditional Medicine
Y1  - 2018
SN  - 97811727769241
PB  - FSP
CY  - Osaka (Japan)
ER  - 
TY  - CHAP
A1  - Köder, Christian
A1  - Englert, Heike
ED  - Serra Majem, Lluis
ED  - Luz Fernández, María
T1  - Influence of a Community-Based Lifestyle Intervention Program Including Recommendations for a Plant-Based Diet on Cardiovascular Risk Parameters
T2  - Nutrients 2019: Nutritional Advances in the Prevention and Management of Chronic Disease
N2  - Background: Cardiovascular disease (CVD) is the leading cause of death in industrialized countries and worldwide. The concentrations of serum total and LDL cholesterol as well as a higher intima media thickness of the common carotid artery (ccIMT) are associated with higher CVD risk. Measuring ccIMT makes it possible to already assess the atherosclerotic process at the subclinical stage. Methods: A two-year nonrandomized, controlled intervention study with 6 times of measurement (baseline; at 10 weeks; at 6, 12, 18, and 24 months). Participants of the intervention group (n = 112) took part in a ten-week intensive lifestyle program (including bi-weekly group sessions, workshops, and personal health coaching at baseline and at 10 weeks), followed by a less intensive phase (monthly lifestyle education group sessions). The control group (n = 87) did not take part in any program. In both groups, CVD-related parameters were assessed, including cholesterol (total, LDL, HDL), ccIMT (not assessed at 10 weeks), as well as health behavior (questionnaires). In between group means were compared with ANOVA using IBM SPSS 24. Results: After 10 weeks, the intervention group showed a reduction in total, LDL, and HDL cholesterol values compared to baseline (p < 0.01). In the control group, these parameters did not change. After 6 months, there was no statistically significant difference in ccIMT change between intervention and control. The 6-month blood results are not available
yet. Conclusion: Our lifestyle program led to clinically relevant reductions in total and LDL cholesterol. Continued follow-up will show whether the improvement of cholesterol levels will be maintained in the intervention group and whether ccIMT will differ between intervention and control.
KW  - cholesterol, lifestyle medicine, intima media thickness, cardiovascular disease, atherosclerosis
Y1  - 2019
UR  - https://nutrients2019.sciforum.net/conferences_files/225/customs/e28f76e450e4716fccaa958564f81120.pdf
SP  - 185
EP  - 185
PB  - MDPI Nutrients 2019 Conference
CY  - Barcelona, Spain
ER  - 
TY  - CHAP
A1  - Husain, Sarah
A1  - Anand, Corinna
A1  - Musiol, Jennifer
A1  - Bordewick-Dell, Ursula
A1  - Englert, Heike
ED  - Majem, Lluis Serra
ED  - Fernández, María Luz
T1  - Effect of a Community-Based Lifestyle Intervention Program on the Blood Plasma Levels of Lipid Peroxidation in a Rural German Population after 10 Weeks of Intensive Intervention
T2  - Nutrients 2019: Nutritional Advances in the Prevention and Management of Chronic Disease
N2  - Lifestyle diseases are linked with hyper-reactivity of inflammatory and immune cells. These cells generate free radicals in the patients, which results in oxidative stress. Recent studies have brought attention to the role of oxidative stress, defined as an imbalance between reactive oxygen species (ROS) and antioxidants. Our research was focused on studying the effects of a community-based lifestyle intervention program on oxidative stress paraments in the plasma of a rural German community. In our study, we examined 105 participants in the intervention group and 70 participants in the control group. The intervention group received 10 weeks of intensive intervention in the form of seminars and workshops. The plasma levels were analyzed at baseline and after 10 weeks of intervention. This is a first-of-itskind study which elucidates the impact of an intensive lifestyle intervention program on the oxidative stress markers in German rural participants. The primary focus of our study was to motivate and encourage participants to switch over toward a healthier lifestyle by improving their knowledge and making them more aware of the principles of healthy living. This may be a useful community program approach, modifiable for different communities by health-services planners in the coming future.
KW  - Oxidative stress, anti-oxidants,free radicals, lipid peroxidation, nutrition, lifestyle,health,intervention,community
Y1  - 2019
UR  - https://nutrients2019.sciforum.net/#custom889
SP  - 219
EP  - 219
PB  - MDPI Nutrients 2019 Conference
CY  - Barcelona, Spain
ER  - 
TY  - CHAP
A1  - Englert, Heike
A1  - Nkengfack, Germaine
A1  - Mahmoudi, Maryam
T1  - Selenium and Immunity
T2  - Nutrition and Immunity. Herausgeber: Maryam Mahmoudi, Nima Rezai, Springer Verlag, 2019
Y1  - 2019
SN  - 978-3-030-16073-9
SP  - 159
EP  - 166
ER  - 
TY  - JOUR
A1  - Merrill, R.
A1  - Aldana, S.
A1  - Greenlaw, R.
A1  - Diehl, H.
A1  - Salberg, A.
A1  - Englert, Heike
T1  - Can Newly Scientific Acquired Healthy Behaviors Persist? An Analysis of Health Behaviour Decay
JF  - Preventing Chronic Disease
Y1  - 2008
SN  - 1545-1151
VL  - 5
IS  - 1
SP  - 13
EP  - 28
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Wegscheider, K.
A1  - Berger, H.
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Reinhold, T.
A1  - Windler, E.
A1  - Katus, HA.
A1  - Willich, SN.
T1  - Productivity loss as a major component of disease-related costs in patients with hypercholesterolemia in Germany
JF  - Clin Res Cardiol
Y1  - 2008
SN  - 1861-0692
VL  - 97
SP  - 152-9
EP  - -
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Wegscheider, K.
A1  - Berger, H.
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Windler, E.
A1  - Katus, H.
A1  - Willich, S.
T1  - Is patient self-report an adequate tool for monitoring cardiovascular conditions in patients with hypercholesterolemia? – Results of the ORBITAL Study
JF  - J Public Health (Oxf)
Y1  - 2010
SN  - 1741-3850
VL  - 32
IS  - 3
SP  - 387
EP  - 394
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Wegscheider, K.
A1  - Berger, H.
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Reinhold, T.
A1  - Windler, E.
A1  - Katus, HA.
A1  - Willich, SN.
T1  - Effect of an adherence-enhancing program on health-related quality of life in patients with hypercholesterolemia
JF  - Eur J Integrative Med
Y1  - 2008
SN  - 1876-3820
VL  - 1
IS  - 1
SP  - 24
EP  - -
ER  - 
TY  - JOUR
A1  - Ahlers, CJ.
A1  - Schaefer, GA.
A1  - Mundt, IA.
A1  - Roll, S.
A1  - Englert, Heike
A1  - Willich, SN.
A1  - Beier, KM.
T1  - How unusual are the contents of paraphilias? Paraphilia-associated sexual arousal patterns in a community-based sample of men
JF  - J Sex Med
Y1  - 2011
SN  - 1743-6095
VL  - 8
SP  - 1362
EP  - 1370
ER  - 
TY  - JOUR
A1  - Nkengfak, G.
A1  - Turimiro, J.
A1  - Nkongang, N.
A1  - Englert, Heike
T1  - A review of nutrition in Cameroon: Food supply, factors influencing nutritional habit and impact on micronutrient (Vitamin A, Iodine, Iron) status
JF  - Les Annales Universitaires de la Faculté de Médécines et des Sciences Biomédicales
Y1  - 2011
SP  - -
EP  - -
ER  - 
TY  - JOUR
A1  - Thieszen, C.
A1  - Aldana, S.
A1  - Diehl, H.
A1  - Mahoney, M.
A1  - Greenlaw, R.
A1  - Vermeersch, D.
A1  - Englert, Heike
T1  - The Coronary Health Improvement Project (CHIP) for Lowering and Improving Psychological Health
JF  - Psychological Reports
N2  - This study extends previous research evaluating the association between the CHIP intervention, change in body weight, and change in psychological health. A randomized controlled health intervention study lasting 4 wk. was used with 348 participants from metropolitan Rockford, Illinois; ages ranged from 24 to 81 yr. Participants were assessed at baseline, 6 wk., and 6 mo. The Beck Depression Inventory (BDI) and three selected psychosocial measures from the SF-36 Health Survey were used. Significantly greater decreases in Body Mass Index (BMI) occurred after 6 wk. and 6 mo. follow-up for the intervention group compared with the control group, with greater decreases for participants in the overweight and obese categories. Significantly greater improvements were observed in BDI scores, role-emotional and social functioning, and mental health throughout follow-up for the intervention group. The greater the decrease in BMI through 6 wk., the better the chance of improved BDI score, role-emotional score, social functioning score, and mental health score, with odds ratios of 1.3 to 1.9. Similar results occurred through 6 mo., except the mental health variable became nonsignificant. These results indicate that the CHIP intervention significantly improved psychological health for at least six months afterwards, in part through its influence on lowering BMI.
Y1  - 2011
SN  - 0033-2941
VL  - 109
IS  - 1
SP  - 338
EP  - 352
ER  - 
TY  - JOUR
A1  - Aldana, S.
A1  - Greenlaw, R.
A1  - Diehl, H.
A1  - Salberg, A.
A1  - Merrill, R. M.
A1  - Englert, Heike
A1  - Jorgenson, R.
T1  - Improvements in Cardiovascular Disease Risk Factors from Lifestyle Change: A Real World Application
JF  - Am J Health Promotion
Y1  - 2007
SN  - 0890-1171
VL  - 21
IS  - 6
SP  - 510
EP  - 516
ER  - 
TY  - JOUR
A1  - Vauth, C.
A1  - Englert, Heike
A1  - Schulenburg, J.
A1  - Greiner, W.
A1  - Fischer, T.
T1  - The economic perspective of sonography in the acute abdomen
JF  - Italian J Public Health
Y1  - 2005
SN  - 1723-7815
VL  - 2
IS  - 1
SP  - 171
EP  - -
ER  - 
TY  - JOUR
A1  - Willich, SN.
A1  - Englert, Heike
A1  - Schäfer, GA.
A1  - Roll, S.
A1  - Beier, KM.
T1  - Association between cardiovascular risk factors and erectile dysfunction – a population-based study
JF  - Eur Heart J
Y1  - 2006
SN  - 0195-668X
VL  - 27 (Suppl.)
SP  - 361
EP  - -
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Diehl, HA.
A1  - Greenlaw, RL.
A1  - Willich, SN.
A1  - Aldana, S.
T1  - The effect of a community-based coronary risk reduction: The Rockford CHIP
JF  - Prev Med
Y1  - 2007
SN  - 1096-0260
VL  - 44
SP  - 513
EP  - 519
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Schäfer, GA.
A1  - Roll, S.
A1  - Ahlers, CJ.
A1  - Beier, K.
A1  - Willich, SN.
T1  - Prevalence of erectile dysfunction among middle-aged men in a metropolitan area in Germany
JF  - Int J Impotence Res
Y1  - 2007
SN  - 0955-9930
VL  - 19
SP  - 183
EP  - 188
ER  - 
TY  - JOUR
A1  - Aldana, S.
A1  - Greenlaw, R.
A1  - Diehl, H.
A1  - Merrill, R.
A1  - Salberg, A.
A1  - Englert, Heike
T1  - A video-based lifestyle intervention and changes in coronary risk
JF  - Health Education Res
Y1  - 2008
SN  - 0268-1153
VL  - 23
IS  - 1
SP  - 115
EP  - 124
ER  - 
TY  - JOUR
A1  - Merrill, R.
A1  - Aldana, S.
A1  - Greenlaw, R.
A1  - Salberg, A.
A1  - Englert, Heike
T1  - Chronic disease risk reduction with a community based lifestyle change program
JF  - Health Education Journal
Y1  - 2008
SN  - 0017-8969
VL  - 67
IS  - 3
SP  - 219
EP  - 230
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Diehl, HA.
A1  - Greenlaw, RL.
T1  - Rationale and Design of the Rockford CHIP, a Community-based Coronary Risk Reduction Program
JF  - Prev Med
Y1  - 2004
SN  - 1096-0260
VL  - 38
SP  - 432
EP  - 441
ER  - 
TY  - JOUR
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Windler, E.
A1  - Meyer-Sabellek, W.
A1  - Katus, H.
A1  - Wegscheider, K.
A1  - Willich, SN.
T1  - Disease-related costs in patients with hypercholesterolemia
JF  - J Epi Community Health
Y1  - 2004
SN  - 0143-005X
VL  - 58 (Suppl.)
SP  - 20
EP  - -
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Vauth, C.
A1  - Fischer, T.
A1  - Greiner, W.
A1  - Willich, S.
T1  - Ultrascound diagnostics in adults and children with acute abdomen
JF  - Italian J Public Health
Y1  - 2005
SN  - 1723-7815
VL  - 2
IS  - 1
SP  - 293
EP  - -
ER  - 
TY  - JOUR
A1  - Aldana, S.
A1  - Greenlaw, R.
A1  - Englert, Heike
A1  - Jackson, R.
A1  - Diehl, H.
T1  - Impact of the Coronary Health Improvement Project (CHIP) on several Employee Populations
JF  - J Occup Environment M
Y1  - 2002
SN  - 1076-2752
VL  - 44
SP  - 9
EP  - 15
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Wirsam, B.
A1  - Leitzmann, C.
T1  - Influence of Lifestyle Intervention on the Dynamic of Lipid Changes Stratified by Apolipoprotein E Geno-Type
JF  - Ann Nutr Metab
Y1  - 2003
SN  - 0250-6807
VL  - 47
SP  - 490
EP  - -
ER  - 
TY  - JOUR
A1  - Willich, SN
A1  - Müller-Nordhorn, J.
A1  - Englert, Heike
A1  - Upmeier, H.
A1  - Meyer-Sabellek, W.
A1  - Wegscheider, K.
T1  - Disease-related costs in patients with hypercholesterolaemia
JF  - Eur Heart J
Y1  - 2003
SN  - 0195-668X
VL  - 24
SP  - 586
EP  - -
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Schaefer, GA.
A1  - Roll, S.
A1  - Beier, K.
A1  - Willich, SN.
T1  - Prevalence of Erectile Dysfunction in a Metrolpolitan Population of Men Aged 40-79
JF  - Gac Sanit
Y1  - 2003
SN  - 1578-1283
VL  - 17 (Suppl 2)
SP  - 175
EP  - -
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Schaefer, GA.
A1  - Roll, S.
A1  - Ahlers, C.
A1  - Beier, K.
A1  - Willich, SN.
T1  - Association between erectile dysfunction and cardiac risk factors in Berlin men aged 40-79
JF  - Biometrical J
Y1  - 2004
SN  - 1521-4036
VL  - 46 (Suppl.)
SP  - 132
EP  - -
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Schaefer, GA.
A1  - Roll, S.
A1  - Beier, KM.
A1  - Willich, SN.
T1  - Results of the Berlin Male Study
JF  - Am J Epidemiol
Y1  - 2004
SN  - 0002-9262
SP  - 90
EP  - -
ER  - 
TY  - JOUR
A1  - Englert, Heike
A1  - Schaefer, GA.
A1  - Roll, S.
A1  - Beier, K.
A1  - Willich, SN.
T1  - The Prevalence of Erectile 		Dysfunction using different Definitions
JF  - J Epi Community Health
Y1  - 2004
SN  - 0143-005X
VL  - 58
SP  - 20
EP  - -
ER  - 
TY  - CHAP
A1  - Koeder, Christian
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - A plant-based diet and healthy lifestyle lower C-reactive protein levels
T2  - Complement Med Res
N2  - Introduction: Many disease processes are accompanied and promoted
by increased inflammation in the body. Increased concentrations of high-sensitivity C-reactive protein (hs-CRP) in the blood are an indicator of subclinical inflammation, increased disease risk, and an increased risk of early death. A healthy plant-based diet and increased physical activity have been shown to reduce hs-CRP concentrations.
Objectives: Our objective was to test if a healthy lifestyle intervention program can improve hs-CRP levels and other risk factors.
Methodology: We are conducting a non-randomized, controlled intervention study with 6 times of measurement (baseline, after 2.5, 6, 12, 18 and 24 months). Participants in the intervention group (n = 104) took part in a 2.5-month intensive lifestyle program focusing on a plant-based diet (PBD), physical activity, stress management and group support. Currently they are in the less intensive phase (monthly seminars) which will be completed after 24 months. The control group (n = 62) did not take part in any program. In both groups hs-CRP was assessed, and participants with an infection/common cold at any of the times of measurement were excluded from the analyses.
Results: In the intervention group (n = 97) we observed a reduction in hsCRP from baseline to 2.5 months (p < 0.001). In the control group (n = 46) hs-CRP levels increased non-significantly. The changes from baseline to 2.5 months were significantly different between intervention and control (p < 0.01).
Conclusion: Our program led to a clinically relevant reduction in hs-CRP.
Continued follow-up will show if this improvement can be maintained in the intervention group. Our study confirms that a PBD and healthier lifestyle choices can lower hs-CRP.
KW  - plant-based diet
KW  - inflammation
KW  - cardiovascular disease
KW  - cancer
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:836-opus-131847
UR  - https://pubmed.ncbi.nlm.nih.gov/33631741/
SP  - 6
EP  - 7
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - Effect of a 6-Month Controlled Lifestyle Intervention on Common Carotid Intima-Media Thickness
JF  - The journal of nutrition, health & aging
KW  - plant-based diet
KW  - cardiovascular disease
KW  - kardiovaskuläre Erkrankungen
KW  - Prävention
Y1  - 2021
U6  - http://dx.doi.org/10.1007/s12603-021-1628-0
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - No clear association of sleep duration or bedtime with common carotid intima-media thickness
JF  - Atherosclerosis
KW  - intima-media thickness, atherosclerosis, cardiovascular disease, sleep, lifestyle medicine
Y1  - 2021
U6  - http://dx.doi.org/10.1016/j.atherosclerosis.2021.06.452
SP  - e150
EP  - e151
ER  - 
TY  - CHAP
A1  - Koeder, Christian
A1  - Husain, Sarah
A1  - Kranz, Ragna-Marie
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - How to achieve sustainable eating in the general population?
T2  - The 9th World Sustainability Forum Program and Abstract Book
N2  - Introduction: Moving towards a more plant-based dietary pattern would likely be beneficial in terms of a variety of sustainability dimensions.
Methodology: We conducted a 2-year intervention study with six measurement time points (baseline, 10 weeks, 6 months, 1 year, 1½ years, 2 years) in rural northwest Germany. The intervention consisted of a lifestyle programme, and dietary recommendations were to move towards a healthy, plant-based diet. The control group received no intervention. Diet quality was assessed with the healthful plant-based diet index (hPDI).
Results: In the intervention group (n = 67), the 2-year trajectory of hPDI was significantly higher compared to control (n = 39; p 0.001; between-group difference: 5.7 (95% CI 4.0, 7.3) food portions/day; adjusted for baseline). The 2-year trajectory of meat intake was significantly lower in the intervention group (n = 79) compared to control (n = 40; p 0.001; between-group difference: -0.7 (95% CI -0.9, -0.5) portions/day; adjusted for baseline).
Conclusion: Our study confirms that plant-based nutrition education in the general population is likely to result in at least modest dietary improvements in terms of general healthfulness and meat reduction.
KW  - plant-based diet
KW  - sustainability
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:836-opus-140455
UR  - https://wsf-9.sciforum.net/
SP  - 57
EP  - 57
PB  - MDPI
ER  - 
TY  - JOUR
A1  - Kranz, Ragna-Marie
A1  - Englert, Heike
T1  - Effect of a community-based lifestyle intervention programme on quality of life among German women
JF  - European Journal of Public Health
N2  - Background
Quality of life is an important concept in the field of health, which can be influenced by various lifestyle factors. The objective was to test if a community-based lifestyle programme would beneficially affect the health-related quality of life of German women.

Methods
The controlled intervention study had a total duration of 24 months. Quality of life (EQ-5D-3L), anthropometrics, vital and blood parameters as well as diagnosed diseases and health economic parameters were collected at baseline (t0), after 10 weeks (t1) and after 6 months (t2). For the intervention group (n = 65) a 10-week intensive lifestyle programme followed by monthly alumni meetings were conducted. The intensive phase consisted of 14 consecutive seminars about a healthy lifestyle, which focused on a plant-based diet, physical activity, stress management and community support. The control group (n = 35) received no intervention.

Results
The first descriptive health profile results of the subgroup analysis showed that 59% women of the intervention group at t0 (t1: 37%; t2: 48%) and 60% of the control group at t0 (t1: 54%; t2: 49%) reported problems in at least one of the EQ-5D dimensions (mobility, selfcare, activities, pain, and anxiety). A significant difference in EQ VAS change between women in intervention (7,15 [95% CI 4,32; 9,98]; EQ VAS t0: 75,35 [SD 13,71]) and control group (-2,63 [95% CI -5,40; 0,15]; EQ VAS t0: 78,80 [SD 18,51]) from t0 to t1 was observed (p < 001; adjusted for baseline). No significant differences in mean EQ VAS change from t0 to t2 and in mean EQ-5D index change from t0 to t1 and t0 to t2 between the groups were observed (p > 0,05; adjusted for baseline).

Conclusions
The preliminary results suggest that the lifestyle intervention programme can have a positive short-time effect on some aspects of quality of life, such as the health profile and EQ VAS. However, the long-term results will be shown in the future.


Key messages

- A healthy lifestyle can affect the quality of life in a positive way.
- The community-based lifestyle programme had a short-time influence on the descriptive health profile and EQ VAS of German women, whereby the EQ index didńt change significantly between the groups.
KW  - health-related quality of life
KW  - plant-based diet
KW  - economics
KW  - community
KW  - healthy lifestyle
Y1  - 2021
U6  - http://dx.doi.org/10.1093/eurpub/ckab165.389
VL  - Volume 31
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - Is fruit intake associated with common carotid intima-media thickness?
JF  - European Journal of Public Health
N2  - Background
Common carotid intima-media thickness (ccIMT) is an established risk marker for cardiovascular events, including myocardial infarction and stroke, which are of high public health relevance. While a higher fruit intake is generally considered beneficial for cardiovascular health, recent studies have shown that a fruit intake of > 2 portions per day may be harmful. Therefore, we tested if there is an association between categories of fruit intake and mean ccIMT.

Methods
We conducted an exploratory, non-prespecified, cross-sectional analysis of baseline values of 167 mostly middle-aged participants of a controlled lifestyle intervention, recruited from the general population in rural northwest Germany (male: n = 58; female: n = 109). Fruit intake was classified into low (<1 portion of fruit/day), intermediate (1-2 portions of fruit/day), and high (>2 portions of fruit/day). Mean ccIMT was measured in accordance with the Mannheim consensus. Between-group differences in mean ccIMT were assessed with analysis of covariance.

Results
Mean age was 57.3 ± 0.7 years (mean ± SEM). Mean fruit intake was 1.6 ± 0.1 portions/day. Average mean ccIMT was 0.679 ± 0.010 mm. There was a significant difference in mean ccIMT between subjects with low (0.676 ± 0.020 mm; n = 50), intermediate (0.653 ± 0.014 mm; n = 72), and high fruit intake (0.724 ± 0.019 mm; n = 45; p = 0.016). But this difference was attenuated when adjusting for age, sex, and homocysteine (p = 0.418).

Conclusions
We found only a non-significant association between consuming >2 portions of fruit per day and ccIMT. Thus, our study could not confirm a negative effect of fruit intake on ccIMT. Age, sex, and homocysteine may confound this association.

Key messages
Current recommendations of 2 portions of fruit per day seem adequate and do not negatively influence carotid intima-media thickness.

Future studies should address confounding of the association between fruit intake and cardiovascular risk markers.
KW  - plant-based diet
KW  - carotid intima-media thickness
KW  - fruit
Y1  - 2021
U6  - http://dx.doi.org/10.1093/eurpub/ckab165.391
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Kranz, Ragna-Marie
A1  - Anand, Corinna
A1  - Husain, Sarah
A1  - Alzughayyar, Dima
A1  - Schoch, Nora
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - Effect of a 1-year controlled lifestyle intervention on body weight and other risk markers (the Healthy Lifestyle Community Programme, cohort 2)
JF  - Obesity Facts
KW  - Adipositas
KW  - Lebensstil
KW  - pflanzenbasierte Ernährung
Y1  - 2021
U6  - http://dx.doi.org/10.1159/000521164
ER  - 
TY  - JOUR
A1  - Kent, Lillian
A1  - Rankin, Paul
A1  - Morton, Darren
A1  - Rankin, Rebekah
A1  - Greenlaw, Roger
A1  - Englert, Heike
T1  - Volunteers: An Effective Medium for Delivering Therapeutic Lifestyle Interventions
JF  - American Journal of Health Promotion
Y1  - 2021
U6  - http://dx.doi.org/10.1177/08901171211062581
ER  - 
TY  - JOUR
A1  - Anand, Corinna
A1  - Kranz, Ragna-Marie
A1  - Husain, Sarah
A1  - Koeder, Christian
A1  - Schoch, Nora
A1  - Karam Alzughayyar, Dima
A1  - Gellner, Reinhold
A1  - Hengst, Karin
A1  - Englert, Heike
T1  - Bridging the gap between science and society: long-term effects of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on weight and the metabolic risk profile: a controlled study
JF  - BMJ Nutrition, Prevention & Health
N2  - Background The potential of adopting a healthy lifestyle to fight non-communicable diseases (NCDs) is not fully used. We hypothesised that the Healthy Lifestyle Community Programme (HLCP, cohort 1) reduces weight and other risk markers compared with baseline and control.

Methods 24-month, non-randomised, controlled intervention trial. Intervention: intensive 8-week phase with seminars, workshops and coaching focusing on a healthy lifestyle (eg, plant-based diet, physical activity, stress management) and group support followed by a 22-month alumni phase. Weight reduction as the primary outcome and other NCD risk parameters were assessed at six time points. Participants were recruited from the general population. Multiple linear regression analyses were conducted.

Results 143 participants (58±12 years, 71% female) were enrolled (91 in the intervention (IG) and 52 in the control group (CG)). Groups’ baseline characteristics were comparable, except participants of IG were younger, more often females, overweight and reported lower energy intake (kcal/day). Weight significantly decreased in IG at all follow-ups by −1.5 ± 1.9 kg after 8 weeks to −1.9 ± 4.0 kg after 24 months and more than in CG (except after 24 months). Being male, in the IG or overweight at baseline and having a university degree predicted more weight loss. After the intervention, there were more participants in the IG with a ‘high’ adherence (+12%) to plant-based food patterns. The change of other risk parameters was most distinct after 8 weeks and in people at elevated risk. Diabetes-related risk parameters did not improve.

Conclusion The HLCP was able to reduce weight and to improve aspects of the NCD risk profile. Weight loss in the IG was moderate but maintained for 24 months. Participants of lower educational status might benefit from even more practical units. Future interventions should aim to include more participants at higher risk.

Trial registration number DRKS00018821.
Y1  - 2022
U6  - http://dx.doi.org/10.1136/bmjnph-2021-000340
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Husain, Sarah
A1  - Kranz, Ragna-Marie
A1  - Anand, Corinna
A1  - Alzughayyar, Dima
A1  - Schoch, Nora
A1  - Hahn, Andrea
A1  - Englert, Heike
T1  - Healthy lifestyle changes favourably affect common carotid intima-media thickness: the Healthy Lifestyle Community Programme (cohort 2)
JF  - Journal of Nutritional Science
N2  - Common carotid intima-media thickness (ccIMT) progression is a risk marker for cardiovascular disease (CVD), whereas healthy lifestyle habits are associated with lower ccIMT. The objective of the present study was to test whether a healthy lifestyle intervention can beneficially affect ccIMT progression. A community-based non-randomised, controlled lifestyle intervention was conducted, focusing on a predominantly plant-based diet (strongest emphasis), physical activity, stress management and social health. Assessments of ccIMT were made at baseline, 6 months and 1 year. Participants had an average age of 57 years and were recruited from the general population in rural northwest Germany (intervention: n 114; control: n 87). From baseline to 1 year, mean ccIMT significantly increased in both the intervention (0⋅026 [95 % CI 0⋅012, 0⋅039] mm) and control group (0⋅045 [95 % CI 0⋅033, 0⋅056] mm). The 1-year trajectory of mean ccIMT was lower in the intervention group (P = 0⋅022; adjusted for baseline). In a subgroup analysis with participants with high baseline mean ccIMT (≥0⋅800 mm), mean ccIMT non-significantly decreased in the intervention group (−0⋅016 [95 % CI −0⋅050, 0⋅017] mm; n 18) and significantly increased in the control group (0⋅065 [95 % CI 0⋅033, 0⋅096] mm; n 12). In the subgroup, the 1-year trajectory of mean ccIMT was significantly lower in the intervention group (between-group difference: −0⋅051 [95 % CI −0⋅075, −0⋅027] mm; P < 0⋅001; adjusted for baseline). The results indicate that healthy lifestyle changes may beneficially affect ccIMT within 1 year, particularly if baseline ccIMT is high.
KW  - plant-based diet
KW  - carotid intima-media thickness
KW  - cardiovascular disease
KW  - atherosclerosis
KW  - lifestyle
Y1  - 2022
UR  - https://www.cambridge.org/core/journals/journal-of-nutritional-science/article/healthy-lifestyle-changes-favourably-affect-common-carotid-intimamedia-thickness-the-healthy-lifestyle-community-programme-cohort-2/DD29870A14031B1EB3DF112B2A381695#article
U6  - http://dx.doi.org/10.1017/jns.2022.46
VL  - 11
ER  - 
TY  - JOUR
A1  - Anand, Corinna
A1  - Hengst, Karin
A1  - Gellner, Reinhold
A1  - Englert, Heike
T1  - Eight weeks of lifestyle change: What are the effects of the Healthy Lifestyle Community Programme (cohort 1) on Cortisol Awakening Response (CAR) and perceived stress?
JF  - Chronic Stress
Y1  - 2022
U6  - http://dx.doi.org/10.1177/24705470221099206
SP  - accepted
ER  - 
TY  - JOUR
A1  - Anand, Corinna
A1  - Hengst, Karin
A1  - Gellner, Reinhold
A1  - Englert, Heike
T1  - Effects of the healthy lifestyle community program (cohort 1) on stress-eating and weight change after 8 weeks: a controlled study
JF  - Scientific Reports
N2  - Stress-eating (eating more or more unhealthily in order to accommodate to stress), contributes to the development and maintenance of obesity. The effect of comprehensive weight loss interventions on changes in stress-eating as well as the contributing role of stress-eating on weight reduction has not been examined. The impact of the 8-week intensive phase of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on emotional, external and restrained eating, as expressions of stress-eating was evaluated in a non-randomized controlled trial. Intervention: 14 seminars (twice per week, including practical units), complemented by stress-regulation and cooking workshops and coaching sessions empowering participants to change their behaviour towards a healthy plant-based diet (ad libitum), stress regulation, regular exercise and to focus on social support. Participants were recruited from the general population. In the intervention group, 91 participants (IG; age: 56 ± 10, 77% female) and in the control group, 52 (CG; age: 62 ± 14, 57% female) were enrolled. At baseline, participants of the IG reported higher levels of stress (9.7 ± 5.4 points [P] vs. 7.6 ± 6.2; p < 0.011), and of emotional eating (27.9 ± 9.4 vs. 20.0 ± 7.1; p < 0.001) and external eating (29.1 ± 4.9 vs. 25.5 ± 5.6; p < 0.001) than participants of the CG. Within 8 weeks, in the IG, scores of emotional eating (− 3.5 ± 5.4 P) and external eating significantly decreased (= − 2.0 ± 3.8 P), while restrained eating increased (2.7 ± 5.0 P; p for all < 0.001). Weight change was negatively correlated with change of external eating (R2 = 0.045; CC = − 0.285; p = 0.014), indicating that a greater weight change was associated with a smaller change of external eating. This is the first study to prospectively investigate the role of stress-eating on the weight reduction effect of comprehensive lifestyle interventions. Our data confirm that overweight is associated with EE and external eating and suggest that the HLCP is capable to reduce both, weight and stress-eating.
KW  - stress-eating, weight, lifestyle
Y1  - 2023
U6  - http://dx.doi.org/10.1038/s41598-022-27063-4
VL  - 13
SP  - 1
EP  - 12
ER  - 
TY  - JOUR
A1  - Anand, Corinna
A1  - Hengst, Karin
A1  - Gellner, Reinhold
A1  - Englert, Heike
T1  - Eight Weeks of Lifestyle Change: What are the Effects of the Healthy Lifestyle Community Programme (Cohort 1) on Cortisol Awakening Response (CAR) and Perceived Stress?
JF  - Chronic stress
N2  - Background: Stress and cortisol dysregulation are linked to NCDs. Moreover, stress favours unhealthy lifestyle patterns, which increase the risk for NCDs. The role of the Cortisol Awakening Response (CAR) and the effect of lifestyle interventions on the same remain unclear. Methods: The impact of the intensive 8-week phase of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on parameters of the CAR, ie cortisol values 0 (sample [S]1), 30), 45 and 60 minutes post-awakening, average peak, S1-peak delta and area under the increase curve (AUCI), and perceived stress levels (PSL) was evaluated in a non-randomized, controlled trial. Covariates of the CAR (eg sleep measures) and irregularities in sampling were assessed. The intervention focussed on stress management, a healthy diet, regular exercise, and social support. Participants were recruited from the general population. Multiple linear regression analyses were conducted. Results: 97 participants (age: 56 ± 10 years; 71% female), with 68 in the intervention group (IG; age: 55 ± 8, 77% female) and 29 participants in the control group (CG; age: 59 ± 12, 59% female), were included in the analysis. The baseline characteristics of both groups were comparable, except participants of IG were younger. On average, the PSL at baseline was low in both groups (IG: 9.7 ± 5.4 points; CG: 8.5 ± 6.9 points; p = .165), but 22% (n = 15) in the IG and 20% (n = 6) in the CG reported a high PSL. Most participants reported irregularities in CAR sampling, eg interruption of sleep (IG: 80% CG: 81%). After 8 weeks, most CAR parameters and the PSL decreased in the IG and CG, resulting in no differences of change between the groups. In the IG only, a decrease of PSL was linked to an increase of CAR parameters, eg AUCI (correlation coefficient = −0.307; p = .017). Conclusion: The HLCP may potentially reduce PSL and change the CAR, but results cannot be clearly attributed to the programme. Methodological challenges and multiple confounders, limit suitability of the CAR in the context of lifestyle interventions. Other measures (eg hair-cortisol) may give further insights. Trial registration: German Clinical Trials Register (DRKS); DRKS00018821; www.drks.de
KW  - cortisol, weight, lifestyle, stress
Y1  - 2022
U6  - http://dx.doi.org/10.1177/24705470221099206
VL  - 2022
IS  - 6
SP  - 1
EP  - 13
ER  - 
TY  - JOUR
A1  - Husain, Sarah
A1  - Hillmann, Katharina
A1  - Hengst, Karin
A1  - Englert, Heike
T1  - Effects of a lifestyle intervention on the biomarkers of oxidative stress in non-communicable diseases: A systematic review
JF  - Frontiers in Aging
N2  - Oxidative stress plays a critical role in the pathogenesis of chronic diseases. Therefore, improvement of oxidative stress status through lifestyle intervention can play a vital role in preventing and treating chronic diseases. This systematic review aims to provide an overview of articles published in the last decade examining the association between lifestyle intervention and oxidative stress biomarkers in the context of non-communicable diseases. The electronic databases PubMed and Web of Science were searched for relevant studies, following the PRISMA (Preferred Reporting of Systematic Reviews and Meta-Analyses) guidelines. This systematic review focused on the four important oxidative stress biomarkers; glutathione (GSH), superoxide dismutase (SOD), catalase, and malondialdehyde. 671 articles were identified, of which nine met the inclusion criteria. A trend emerged, showing that lifestyle modifications that focus on diet and physical health can improve oxidative stress in the form of an increase in superoxide dismutase and CAT levels and a decrease in Malondialdehyde levels in participants with non-communicable diseases (NCDs), GSH levels were not affected. However, the results are difficult to compare because of the heterogeneity of the methods of the biomarkers studied. Our review indicates that oxidative stress can be influenced by lifestyle modifications and may be an effective tool for the prevention and management of non-communicable diseases. This review also elucidated the importance of analyzing multiple oxidative stress biomarkers to evaluate oxidative stress, it further highlights the need to conduct long-term lifestyle intervention studies on oxidative stress biomarkers to understand the connection between oxidative stress biomarkers, NCDs and Lifestyle intervention.
KW  - oxidative stress, lifestyle intervention, lifestyle diseases, antioxidants, non-communicable diseases, prevention, ageing, immunity
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:836-opus-160827
PB  - Frontiers Journal
CY  - Germany
ER  - 
TY  - JOUR
A1  - Koeder, Christian
A1  - Anand, Corinna
A1  - Husain, Sarah
A1  - Kranz, Ragna-Marie
A1  - Schoch, Nora
A1  - Alzughayyar, Dima
A1  - Bitterlich, Norman
A1  - Hahn, Andreas
A1  - Englert, Heike
T1  - Exploratory analysis of the effect of a controlled lifestyle intervention on inflammatory markers – the Healthy Lifestyle Community Programme (cohort 2)
JF  - BMC Nutrition
N2  - Background
Chronic low-grade inflammation is associated with an increased risk of chronic disease and mortality. The objective of the study was to test the effect of a healthy lifestyle intervention on biomarkers of inflammation (among other risk markers).

Methods
We conducted a non-randomized controlled trial with mostly middle-aged and elderly participants from the general population in rural northwest Germany (intervention: n = 114; control: n = 87). The intervention consisted of a 1-year lifestyle programme focusing on diet (largely plant-based; strongest emphasis), physical activity, stress management, and social support. High-sensitivity C-reactive protein (hs-CRP) was assessed at baseline, 10 weeks, 6 months, and 1 year. Homocysteine (Hcy) was assessed at baseline, 10 weeks, and 1 year. Adiponectin (Apn) was assessed at baseline and 10 weeks. An exploratory analysis of these inflammatory markers assessing the between-group differences with ANCOVA was conducted.

Results
The 1-year trajectory of hs-CRP was significantly lower in the intervention group compared to control (between-group difference: -0.8 (95% CI -1.2, -0.3) mg/l; p = 0.001; adjusted for baseline). The 1-year trajectory of Hcy was non-significantly higher in the intervention compared to control (between-group difference: 0.2 (95% CI -0.3, 0.7) µmol/l; p = 0.439; adjusted for baseline). From baseline to 10 weeks, Apn decreased significantly more in the intervention group compared to control (between-group difference: -1.6 (95% CI -2.7, -0.5) µg/ml; p = 0.004; adjusted for baseline).

Conclusions
Our study shows that healthy lifestyle changes can lower hs-CRP and Apn levels and are unlikely to significantly affect Hcy levels within 1 year.
Trial registration

German Clinical Trials Register (DRKS; reference: DRKS00018775, registered 12 Sept 2019; retrospectively registered; www.drks.de).
Y1  - 2023
U6  - http://dx.doi.org/10.1186/s40795-023-00684-2
SN  - 2055-0928
VL  - 9
IS  - 25
ER  - 
TY  - CHAP
A1  - Englert, Heike
A1  - Diehl, H.
A1  - Greenlaw, R.
A1  - Aldana, S.
T1  - The Effects of Lifestyle Modification on Glycemic Levels and Medication Intake:The Rockford CHIP
T2  - Dr. Oreste Capelli, Primary Care at a Glance - Hot Topics and New Insights
N2  - Introduction: The high prevalence of cardiovascular disease (CVD) in the past 50 years has led to intense research, resulting in many improvements in treatment. At the same time, type 2 diabetes, with its concomitant increase in vascular complications, has become a serious, exploding and costly public health concern . Diabetes now affects 285 million adults worldwide and 344 million with pre-diabetes. Of these, 25.8 million diabetics and 79 million pre-diabetics are found in the United States alone.The current cost of diabetes in the US is likely to exceed the $174 billion estimate, which includes 2/3 for direct medical costs and 1/3 for indirect costs, such as disability, work loss, and premature death, but omits the social cost of intangibles (e.g. pain, suffering, lower quality of life). The diabetes epidemic has been accompanied by a similarly drastic increase in obesity. Although the relationship between the two developments is a matter of debate, both are presumably caused by changes in dietary habits and an increasingly sedentary modern lifestyle . Compelling evidence has shown that lifestyle changes can effectively prevent or delay the occurrence of type 2 diabetes. Because individuals at risk for this disease can usually be identified during the pre-diabetic phase of impaired glucose tolerance, early intervention and lifestyle change offer a logical approach to preventing this disease and its devastating vascular complications. Additionally, community-based lifestyle interventions for high risk groups and for the general population are a cost-effective way of curbing the growing burden of the disease. Solidifying the scientific basis for the prevention, treatment and control of this disease and its implementation on a national level, however, remains a difficult challenge. Moreresearch is needed to provide comprehensive and more effective strategies for weight-loss,especially over time. Therefore, the objectives of this study were to identify diabetics and those at risk (prediabetics) out of the total cohort of 1,517 who selected themselves into an intensive community-based lifestyle intervention program, and to assess its clinical efficacy ineffecting medication status as determined and managed by their personal physicians.
Y1  - 2012
SN  - 979-953-307-556-2
U6  - http://dx.doi.org/10.25974/fhms-571
SP  - 323
EP  - 336
PB  - InTech
CY  - Rijeka, Rumänien
ER  - 
TY  - JOUR
A1  - Nkengfak, G.
A1  - Torimiro, J.
A1  - Nkongang, N.
A1  - Englert, Heike
T1  - A review: Effects of antioxidants on CD4 and viral load in HIV-infected women in sub-Saharan Africa - dietary supplements vs. local diet.
JF  - International Journal for Vitamin and Nutrition Research
N2  - Abstract In sub-Sahara Africa, micronutrient deficiency, especially of antioxidant micronutrients including vitamins A, C, and E, beta-carotene, selenium, zinc, and polyphenols is very common in HIV-positive patients. Amongst adults, women are the most vulnerable. Antioxidants are known to play a vital role in the immune system, reducing oxidative stress. Oxidative stress is induced by excess production of reactive oxygen species (ROS), due to the HIV infection. Such damage may be prevented or moderated through adequate oral intake of antioxidants, scavenging ROS, as well as protecting cells and tissues against oxidative stress. Antioxidants can be provided to the body through locally available antioxidant rich-diets such as fruit-and-vegetable-based diets and/or dietary supplements. Provision of antioxidants through local diets or dietary supplements exercise beneficial effects on biological markers of the immune system (CD4 and viral load). However, while dietary supplements represent a costly and short-term strategy to limiting antioxidant deficiency, local diets, combined with adequate nutritional education, can provide a low-cost and long-term strategy to reduce oxidative stress, prevent micronutrient deficiency, and slow down HIV disease progression. The former can be applicable in countries around the West, Central, and South coast of Africa, which are rich in natural food resources. In contrast with significant evidence that dietary supplements confer benefits in HIV patients, fewer data are available relating to the benefits of local diets. Thus the need to do more research in this area arises. This review compares available data on effects of antioxidants on CD4 and viral load in HIV-positive women noneligible for antiretroviral therapy. Intake of antioxidants though dietary supplements and local diet, associated with nutritional education, is compared. Studies conducted in sub-Sahara Africa are considered.
Y1  - 2012
SN  - 0300-9831
VL  - 82
SP  - 63
EP  - 72
ER  - 
TY  - JOUR
A1  - Willich, S. N.
A1  - Englert, Heike
A1  - Sonntag, F.
A1  - Völler, H.
A1  - Meyer-Sabellek, W.
A1  - Wegscheider, K.
A1  - Windler, E.
A1  - Katus, H. A.
A1  - Müller-Nordhorn, J.
T1  - Impact of a compliance program on cholesterol control: results of the randomized ORBITAL study in 8108 patients treated with rosuvastatin
JF  - Eur J Cardiovasc Prev Rehabil
N2  - Abstract This study extends previous research evaluating the association between the CHIP intervention, change in body weight, and change in psychological health. A randomized controlled health intervention study lasting 4 wk. was used with 348 participants from metropolitan Rockford, Illinois; ages ranged from 24 to 81 yr. Participants were assessed at baseline, 6 wk., and 6 mo. The Beck Depression Inventory (BDI) and three selected psychosocial measures from the SF-36 Health Survey were used. Significantly greater decreases in Body Mass Index (BMI) occurred after 6 wk. and 6 mo. follow-up for the intervention group compared with the control group, with greater decreases for participants in the overweight and obese categories. Significantly greater improvements were observed in BDI scores, role-emotional and social functioning, and mental health throughout follow-up for the intervention group. The greater the decrease in BMI through 6 wk., the better the chance of improved BDI score, role-emotional score, social functioning score, and mental health score, with odds ratios of 1.3 to 1.9. Similar results occurred through 6 mo., except the mental health variable became nonsignificant. These results indicate that the CHIP intervention significantly improved psychological health for at least six months afterwards, in part through its influence on lowering BMI.
Y1  - 2009
VL  - 16
SP  - 180
EP  - 187
ER  - 
TY  - JOUR
A1  - Kranz, Ragna-Marie
A1  - Kettler, Carmen
A1  - Koeder, Christian
A1  - Husain, Sarah
A1  - Anand, Corinna
A1  - Schoch, Nora
A1  - Englert, Heike
T1  - Health Economic Evaluation of a Controlled Lifestyle Intervention: The Healthy Lifestyle Community Program (Cohort 2; HLCP-2)
JF  - Nutrients
N2  - Non-communicable diseases (NCD) are associated with high costs for healthcare systems. We evaluated changes in total costs, comprising direct and indirect costs, due to a 24-month non-randomized, controlled lifestyle intervention trial with six measurement time points aiming to improve the risk profile for NCDs. Overall, 187 individuals from the general population aged ≥18 years were assigned to either the intervention group (IG; n = 112), receiving a 10-week intensive lifestyle intervention focusing on a healthy, plant-based diet; physical activity; stress management; and community support, followed by a 22-month follow-up phase including monthly seminars, or a control group (CG; n = 75) without intervention. The complete data sets of 118 participants (IG: n = 79; CG: n = 39) were analyzed. At baseline, total costs per person amounted to 67.80 ± 69.17 EUR in the IG and 48.73 ± 54.41 EUR in the CG per week. The reduction in total costs was significantly greater in the IG compared to the CG after 10 weeks (p = 0.012) and 6 months (p = 0.004), whereas direct costs differed significantly after 10 weeks (p = 0.017), 6 months (p = 0.041) and 12 months (p = 0.012) between the groups. The HLCP-2 was able to reduce health-related economic costs, primarily due to the reduction in direct costs.
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:836-opus-174544
ER  -