@article{SchuppDammFothetal.2020, author = {Schupp, Thomas and Damm, Georg and Foth, Heidi and Freyberger, Alexius and Gebel, Thomas and Gundert-Remy, Ursula and Hengstler, Jan G. and Mangerich, Aswin and Partosch, Falko and R{\"o}hl, Claudia and Wollin, Klaus-Michael}, title = {Long‑term simulation of lead concentrations in agricultural soils in relation to human adverse health effects}, series = {Archives of Toxicology}, volume = {94 / 2020}, journal = {Archives of Toxicology}, doi = {https://doi.org/10.1007/s00204-020-02762-x}, pages = {2319 -- 2329}, year = {2020}, abstract = {Lead (Pb) exposure of consumers and the environment has been reduced over the past decades. Despite all measures taken, immission of Pb onto agricultural soils still occurs, with fertilizer application, lead shot from hunting activities, and Pb from air deposition representing major sources. Little is known about the intermediate and long-term consequences of these emissions. To gain more insight, we established a mathematical model that considers input from fertilizer, ammunition, deposition from air, uptake of Pb by crops, and wash-out to simulate the resulting Pb concentrations in soil over extended periods. In a further step, human oral exposure by crop-based food was simulated and blood concentrations were derived to estimate the margin of exposure to Pb-induced toxic effects. Simulating current farming scenarios, a new equilibrium concentration of Pb in soil would be established after several centuries. Developmental neurotoxicity represents the most critical toxicological effect of Pb for humans. According to our model, a Pb concentration of ~ 5 mg/kg in agricultural soil leads to an intake of approximately 10 μg Pb per person per day by the consumption of agricultural products, the dose corresponding to the tolerable daily intake (TDI). Therefore, 5 mg Pb/kg represents a critical concentration in soil that should not be exceeded. Starting with a soil concentration of 0.1 mg/kg, the current control level for crop fields, our simulation predicts periods of ~ 50 and ~ 175 years for two Pb immission scenarios for mass of Pb per area and year [scenario 1: ~ 400 g Pb/(ha × a); scenario 2: ~ 175 g Pb/(ha × a)], until the critical concentration of ~ 5 mg/kg Pb in soil would be reached. The two scenarios, which differ in their Pb input via fertilizer, represent relatively high but not unrealistic Pb immissions. From these scenarios, we calculated that the annual deposition of Pb onto soil should remain below ~ 100 g/(ha × a) in order not to exceed the critical soil level of 5 mg/kg. We propose as efficient measures to reduce Pb input into agricultural soil to lower the Pb content of compost and to use alternatives to Pb ammunition for hunting.}, language = {en} } @book{Schupp2020, author = {Schupp, Thomas}, title = {Hazardous substances}, publisher = {De Gruyter}, address = {Berlin}, isbn = {978-3-11-061805-1}, publisher = {FH M{\"u}nster - University of Applied Sciences}, pages = {375}, year = {2020}, abstract = {This title presents a detailed overview on the full range of hazard categories and the associated risks of chemicals. It provides a basic introduction into toxicology, ecotoxicology and environmental behavior and enables all who perform precise chemical analysis to handle substances according to their intrinsic properties such as physical-chemical, environmental, ecological and toxicological hazards.}, language = {en} } @article{BoeingSandtenHrinciusetal.2021, author = {Boeing, Christian and Sandten, Christian and Hrincius, Eike R. and Anhlan, Darisuren and Dworog, Andreas and Hanning, Stephanie and Kuennemann, Thilo and Niehues, Christopher and Schupp, Thomas and Stec, Edyta and Thume, Julius and Triphaus, Daniel and Wilkens, Markus and Uphoff, Holger and Zuendorf, Josef and Jacobshagen, Anja and Kreyenschmidt, Martin and Ludwig, Stephan and Mertins, Hans-Christoph and Mellmann, Alexander}, title = {Decontamination of disposable respirators for reuse in a pandemic employing in-situ-generated peracetic acid}, series = {AJIC: American Journal of Infection Control}, volume = {2021}, journal = {AJIC: American Journal of Infection Control}, number = {September 22}, issn = {0196-6553}, doi = {10.1016/j.ajic.2021.09.017}, year = {2021}, abstract = {Background During shortages of filtering face pieces (FFP) in a pandemic, it is necessary to implement a method for safe reuse or extended use. Our aim was to develop a simple, inexpensive and ecological method for decontamination of disposable FFPs that preserves filtration efficiency and material integrity.}, language = {en} } @article{SandtenBoeingHrinciusetal.2021, author = {Sandten, Christian Stefan and B{\"o}ing, Christian and Hrincius, Eike and Anhlan, Darisuren and Kreyenschmidt, Martin and Ludwig, Stephan and Mertins, Hans-Christoph and Mellmann, Alexander and Dworog, Andreas and Hanning, Stephanie and Kuennemann, Thilo and Niehues, Christopher and Schupp, Thomas and Stec, Edyta and Thume, Julius and Triphaus, Daniel and Wilkern, Markus and Uphoff, Holger and Z{\"u}ndorf, Josef and Jacobshagen, Anja}, title = {Decontamination of disposable respirators for reuse in a pandemic employing in-situ-generated peracetic acid}, series = {American Journal of Infection Control}, volume = {00 / 2021}, journal = {American Journal of Infection Control}, doi = {10.1016/j.ajic.2021.09.017}, pages = {1 -- 7}, year = {2021}, language = {en} }