@inproceedings{KettlerKranzAnandetal.2024, author = {Kettler, Carmen and Kranz, Ragna-Marie and Anand, Corinna and Husain, Sarah and K{\"o}der, Christian and Michaelsen, Maren M. and Esch, Tobias and Englert, Heike}, title = {Effekt eines community-basierten Lebensstil-Interventionsprogramms auf die Selbstwirksamkeitserwartung von B{\"u}rger*innen in Bezug auf eine gesunde Ern{\"a}hrung}, series = {Proceedings of the German Nutrition Society}, booktitle = {Proceedings of the German Nutrition Society}, publisher = {Deutsche Gesellschaft f{\"u}r Ern{\"a}hrung e.V. (DGE)}, address = {Bonn}, pages = {93 -- 93}, year = {2024}, language = {de} } @article{AnandHengstGellneretal.2023, author = {Anand, Corinna and Hengst, Karin and Gellner, Reinhold and Englert, Heike}, title = {Effects of the healthy lifestyle community program (cohort 1) on stress-eating and weight change after 8 weeks: a controlled study}, series = {Scientific Reports}, volume = {13}, journal = {Scientific Reports}, doi = {10.1038/s41598-022-27063-4}, pages = {1 -- 12}, year = {2023}, abstract = {Stress-eating (eating more or more unhealthily in order to accommodate to stress), contributes to the development and maintenance of obesity. The effect of comprehensive weight loss interventions on changes in stress-eating as well as the contributing role of stress-eating on weight reduction has not been examined. The impact of the 8-week intensive phase of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on emotional, external and restrained eating, as expressions of stress-eating was evaluated in a non-randomized controlled trial. Intervention: 14 seminars (twice per week, including practical units), complemented by stress-regulation and cooking workshops and coaching sessions empowering participants to change their behaviour towards a healthy plant-based diet (ad libitum), stress regulation, regular exercise and to focus on social support. Participants were recruited from the general population. In the intervention group, 91 participants (IG; age: 56 ± 10, 77\% female) and in the control group, 52 (CG; age: 62 ± 14, 57\% female) were enrolled. At baseline, participants of the IG reported higher levels of stress (9.7 ± 5.4 points [P] vs. 7.6 ± 6.2; p < 0.011), and of emotional eating (27.9 ± 9.4 vs. 20.0 ± 7.1; p < 0.001) and external eating (29.1 ± 4.9 vs. 25.5 ± 5.6; p < 0.001) than participants of the CG. Within 8 weeks, in the IG, scores of emotional eating (- 3.5 ± 5.4 P) and external eating significantly decreased (= - 2.0 ± 3.8 P), while restrained eating increased (2.7 ± 5.0 P; p for all < 0.001). Weight change was negatively correlated with change of external eating (R2 = 0.045; CC = - 0.285; p = 0.014), indicating that a greater weight change was associated with a smaller change of external eating. This is the first study to prospectively investigate the role of stress-eating on the weight reduction effect of comprehensive lifestyle interventions. Our data confirm that overweight is associated with EE and external eating and suggest that the HLCP is capable to reduce both, weight and stress-eating.}, language = {en} } @article{KoederAnandHusainetal.2023, author = {Koeder, Christian and Anand, Corinna and Husain, Sarah and Kranz, Ragna-Marie and Schoch, Nora and Alzughayyar, Dima and Bitterlich, Norman and Hahn, Andreas and Englert, Heike}, title = {Exploratory analysis of the effect of a controlled lifestyle intervention on inflammatory markers - the Healthy Lifestyle Community Programme (cohort 2)}, series = {BMC Nutrition}, volume = {9}, journal = {BMC Nutrition}, number = {25}, issn = {2055-0928}, doi = {10.1186/s40795-023-00684-2}, year = {2023}, abstract = {Background Chronic low-grade inflammation is associated with an increased risk of chronic disease and mortality. The objective of the study was to test the effect of a healthy lifestyle intervention on biomarkers of inflammation (among other risk markers). Methods We conducted a non-randomized controlled trial with mostly middle-aged and elderly participants from the general population in rural northwest Germany (intervention: n = 114; control: n = 87). The intervention consisted of a 1-year lifestyle programme focusing on diet (largely plant-based; strongest emphasis), physical activity, stress management, and social support. High-sensitivity C-reactive protein (hs-CRP) was assessed at baseline, 10 weeks, 6 months, and 1 year. Homocysteine (Hcy) was assessed at baseline, 10 weeks, and 1 year. Adiponectin (Apn) was assessed at baseline and 10 weeks. An exploratory analysis of these inflammatory markers assessing the between-group differences with ANCOVA was conducted. Results The 1-year trajectory of hs-CRP was significantly lower in the intervention group compared to control (between-group difference: -0.8 (95\% CI -1.2, -0.3) mg/l; p = 0.001; adjusted for baseline). The 1-year trajectory of Hcy was non-significantly higher in the intervention compared to control (between-group difference: 0.2 (95\% CI -0.3, 0.7) µmol/l; p = 0.439; adjusted for baseline). From baseline to 10 weeks, Apn decreased significantly more in the intervention group compared to control (between-group difference: -1.6 (95\% CI -2.7, -0.5) µg/ml; p = 0.004; adjusted for baseline). Conclusions Our study shows that healthy lifestyle changes can lower hs-CRP and Apn levels and are unlikely to significantly affect Hcy levels within 1 year. Trial registration German Clinical Trials Register (DRKS; reference: DRKS00018775, registered 12 Sept 2019; retrospectively registered; www.drks.de).}, language = {en} } @article{AnandKranzHusainetal.2022, author = {Anand, Corinna and Kranz, Ragna-Marie and Husain, Sarah and Koeder, Christian and Schoch, Nora and Karam Alzughayyar, Dima and Gellner, Reinhold and Hengst, Karin and Englert, Heike}, title = {Bridging the gap between science and society: long-term effects of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on weight and the metabolic risk profile: a controlled study}, series = {BMJ Nutrition, Prevention \& Health}, journal = {BMJ Nutrition, Prevention \& Health}, doi = {10.1136/bmjnph-2021-000340}, year = {2022}, abstract = {Background The potential of adopting a healthy lifestyle to fight non-communicable diseases (NCDs) is not fully used. We hypothesised that the Healthy Lifestyle Community Programme (HLCP, cohort 1) reduces weight and other risk markers compared with baseline and control. Methods 24-month, non-randomised, controlled intervention trial. Intervention: intensive 8-week phase with seminars, workshops and coaching focusing on a healthy lifestyle (eg, plant-based diet, physical activity, stress management) and group support followed by a 22-month alumni phase. Weight reduction as the primary outcome and other NCD risk parameters were assessed at six time points. Participants were recruited from the general population. Multiple linear regression analyses were conducted. Results 143 participants (58±12 years, 71\% female) were enrolled (91 in the intervention (IG) and 52 in the control group (CG)). Groups' baseline characteristics were comparable, except participants of IG were younger, more often females, overweight and reported lower energy intake (kcal/day). Weight significantly decreased in IG at all follow-ups by -1.5 ± 1.9 kg after 8 weeks to -1.9 ± 4.0 kg after 24 months and more than in CG (except after 24 months). Being male, in the IG or overweight at baseline and having a university degree predicted more weight loss. After the intervention, there were more participants in the IG with a 'high' adherence (+12\%) to plant-based food patterns. The change of other risk parameters was most distinct after 8 weeks and in people at elevated risk. Diabetes-related risk parameters did not improve. Conclusion The HLCP was able to reduce weight and to improve aspects of the NCD risk profile. Weight loss in the IG was moderate but maintained for 24 months. Participants of lower educational status might benefit from even more practical units. Future interventions should aim to include more participants at higher risk. Trial registration number DRKS00018821.}, language = {en} } @article{KoederHusainKranzetal.2022, author = {Koeder, Christian and Husain, Sarah and Kranz, Ragna-Marie and Anand, Corinna and Alzughayyar, Dima and Schoch, Nora and Hahn, Andrea and Englert, Heike}, title = {Healthy lifestyle changes favourably affect common carotid intima-media thickness: the Healthy Lifestyle Community Programme (cohort 2)}, series = {Journal of Nutritional Science}, volume = {11}, journal = {Journal of Nutritional Science}, doi = {10.1017/jns.2022.46}, year = {2022}, abstract = {Common carotid intima-media thickness (ccIMT) progression is a risk marker for cardiovascular disease (CVD), whereas healthy lifestyle habits are associated with lower ccIMT. The objective of the present study was to test whether a healthy lifestyle intervention can beneficially affect ccIMT progression. A community-based non-randomised, controlled lifestyle intervention was conducted, focusing on a predominantly plant-based diet (strongest emphasis), physical activity, stress management and social health. Assessments of ccIMT were made at baseline, 6 months and 1 year. Participants had an average age of 57 years and were recruited from the general population in rural northwest Germany (intervention: n 114; control: n 87). From baseline to 1 year, mean ccIMT significantly increased in both the intervention (0⋅026 [95 \% CI 0⋅012, 0⋅039] mm) and control group (0⋅045 [95 \% CI 0⋅033, 0⋅056] mm). The 1-year trajectory of mean ccIMT was lower in the intervention group (P = 0⋅022; adjusted for baseline). In a subgroup analysis with participants with high baseline mean ccIMT (≥0⋅800 mm), mean ccIMT non-significantly decreased in the intervention group (-0⋅016 [95 \% CI -0⋅050, 0⋅017] mm; n 18) and significantly increased in the control group (0⋅065 [95 \% CI 0⋅033, 0⋅096] mm; n 12). In the subgroup, the 1-year trajectory of mean ccIMT was significantly lower in the intervention group (between-group difference: -0⋅051 [95 \% CI -0⋅075, -0⋅027] mm; P < 0⋅001; adjusted for baseline). The results indicate that healthy lifestyle changes may beneficially affect ccIMT within 1 year, particularly if baseline ccIMT is high.}, language = {en} } @article{AnandHengstGellneretal.2022, author = {Anand, Corinna and Hengst, Karin and Gellner, Reinhold and Englert, Heike}, title = {Eight weeks of lifestyle change: What are the effects of the Healthy Lifestyle Community Programme (cohort 1) on Cortisol Awakening Response (CAR) and perceived stress?}, series = {Chronic Stress}, journal = {Chronic Stress}, doi = {10.1177/24705470221099206}, pages = {accepted}, year = {2022}, language = {en} } @article{AnandHengstGellneretal.2022, author = {Anand, Corinna and Hengst, Karin and Gellner, Reinhold and Englert, Heike}, title = {Eight Weeks of Lifestyle Change: What are the Effects of the Healthy Lifestyle Community Programme (Cohort 1) on Cortisol Awakening Response (CAR) and Perceived Stress?}, series = {Chronic stress}, volume = {2022}, journal = {Chronic stress}, number = {6}, doi = {10.1177/24705470221099206}, pages = {1 -- 13}, year = {2022}, abstract = {Background: Stress and cortisol dysregulation are linked to NCDs. Moreover, stress favours unhealthy lifestyle patterns, which increase the risk for NCDs. The role of the Cortisol Awakening Response (CAR) and the effect of lifestyle interventions on the same remain unclear. Methods: The impact of the intensive 8-week phase of the Healthy Lifestyle Community Programme (HLCP, cohort 1) on parameters of the CAR, ie cortisol values 0 (sample [S]1), 30), 45 and 60 minutes post-awakening, average peak, S1-peak delta and area under the increase curve (AUCI), and perceived stress levels (PSL) was evaluated in a non-randomized, controlled trial. Covariates of the CAR (eg sleep measures) and irregularities in sampling were assessed. The intervention focussed on stress management, a healthy diet, regular exercise, and social support. Participants were recruited from the general population. Multiple linear regression analyses were conducted. Results: 97 participants (age: 56 ± 10 years; 71\% female), with 68 in the intervention group (IG; age: 55 ± 8, 77\% female) and 29 participants in the control group (CG; age: 59 ± 12, 59\% female), were included in the analysis. The baseline characteristics of both groups were comparable, except participants of IG were younger. On average, the PSL at baseline was low in both groups (IG: 9.7 ± 5.4 points; CG: 8.5 ± 6.9 points; p = .165), but 22\% (n = 15) in the IG and 20\% (n = 6) in the CG reported a high PSL. Most participants reported irregularities in CAR sampling, eg interruption of sleep (IG: 80\% CG: 81\%). After 8 weeks, most CAR parameters and the PSL decreased in the IG and CG, resulting in no differences of change between the groups. In the IG only, a decrease of PSL was linked to an increase of CAR parameters, eg AUCI (correlation coefficient = -0.307; p = .017). Conclusion: The HLCP may potentially reduce PSL and change the CAR, but results cannot be clearly attributed to the programme. Methodological challenges and multiple confounders, limit suitability of the CAR in the context of lifestyle interventions. Other measures (eg hair-cortisol) may give further insights. Trial registration: German Clinical Trials Register (DRKS); DRKS00018821; www.drks.de}, language = {en} } @article{KoederAlzughayyarAnandetal.2022, author = {Koeder, Christian and Alzughayyar, Dima and Anand, Corinna and Kranz, Ragna-Marie and Husain, Sarah and Schoch, Nora and Hahn, Andreas and Englert, Heike}, title = {The healthful plant-based diet index as a tool for obesity prevention - the Healthy Lifestyle Community Program cohort 3 study}, series = {Obesity Science and Practice}, journal = {Obesity Science and Practice}, doi = {10.1002/osp4.649}, year = {2022}, abstract = {Background Worldwide the prevalence of obesity is high, and promoting a shift towards more healthful and more plant-based dietary patterns appears to be one promising strategy to address this issue. A dietary score to assess adherence to a healthy plant-based diet is the healthful plant-based diet index. While there is evidence from cohort studies that an increased healthful plant-based diet index is associated with improved risk markers, evidence from intervention studies is still lacking. Methods A lifestyle intervention was conducted with mostly middle-aged and elderly participants from the general population (n = 115). The intervention consisted of a 16-month lifestyle program focusing on a healthy plant-based diet, physical activity, stress management, and community support. Results After 10 weeks, significant improvements were seen in dietary quality, body weight, body mass index, waist circumference, total cholesterol, measured and calculated LDL cholesterol, oxidized LDL particles, non-HDL cholesterol, remnant cholesterol, glucose, insulin, blood pressure, and pulse pressure. After 16 months, significant decreases were seen in body weight (-1.8 kg), body mass index (-0.6 kg/m2), and measured LDL cholesterol (-12 mg/dl). Increases in the healthful plant-based diet index were associated with risk marker improvements. Conclusions The recommendation of moving towards a plant-based diet appears acceptable and actionable and may improve body weight. The healthful plant-based diet index can be a useful parameter for intervention studies.}, language = {de} } @article{KoederHahnEnglert2021, author = {Koeder, Christian and Hahn, Andreas and Englert, Heike}, title = {Effect of a 6-Month Controlled Lifestyle Intervention on Common Carotid Intima-Media Thickness}, series = {The journal of nutrition, health \& aging}, journal = {The journal of nutrition, health \& aging}, doi = {10.1007/s12603-021-1628-0}, year = {2021}, language = {en} } @incollection{EnglertAnandKoeder2021, author = {Englert, Heike and Anand, Corinna and K{\"o}der, Christian}, title = {Das Healthy-Lifestyle-Community-Programm: ein Community-basiertes, ganzheitliches Lebensstil-Interventionsprojekt zum gesunden Leben und Arbeiten}, series = {Gesundheitsf{\"o}rderung und Versorgung im l{\"a}ndlichen Raum: Grundlagen, Strategien und Interventionskonzepte}, booktitle = {Gesundheitsf{\"o}rderung und Versorgung im l{\"a}ndlichen Raum: Grundlagen, Strategien und Interventionskonzepte}, publisher = {Hogrefe}, isbn = {9783456859798}, doi = {10.1024/85979-000}, publisher = {FH M{\"u}nster - University of Applied Sciences}, pages = {295 -- 308}, year = {2021}, language = {de} } @article{KoederHahnEnglert2021, author = {Koeder, Christian and Hahn, Andreas and Englert, Heike}, title = {No clear association of sleep duration or bedtime with common carotid intima-media thickness}, series = {Atherosclerosis}, journal = {Atherosclerosis}, doi = {10.1016/j.atherosclerosis.2021.06.452}, pages = {e150 -- e151}, year = {2021}, language = {en} } @article{KranzEnglert2021, author = {Kranz, Ragna-Marie and Englert, Heike}, title = {Effect of a community-based lifestyle intervention programme on quality of life among German women}, series = {European Journal of Public Health}, volume = {Volume 31}, journal = {European Journal of Public Health}, doi = {10.1093/eurpub/ckab165.389}, year = {2021}, abstract = {Background Quality of life is an important concept in the field of health, which can be influenced by various lifestyle factors. The objective was to test if a community-based lifestyle programme would beneficially affect the health-related quality of life of German women. Methods The controlled intervention study had a total duration of 24 months. Quality of life (EQ-5D-3L), anthropometrics, vital and blood parameters as well as diagnosed diseases and health economic parameters were collected at baseline (t0), after 10 weeks (t1) and after 6 months (t2). For the intervention group (n = 65) a 10-week intensive lifestyle programme followed by monthly alumni meetings were conducted. The intensive phase consisted of 14 consecutive seminars about a healthy lifestyle, which focused on a plant-based diet, physical activity, stress management and community support. The control group (n = 35) received no intervention. Results The first descriptive health profile results of the subgroup analysis showed that 59\% women of the intervention group at t0 (t1: 37\%; t2: 48\%) and 60\% of the control group at t0 (t1: 54\%; t2: 49\%) reported problems in at least one of the EQ-5D dimensions (mobility, selfcare, activities, pain, and anxiety). A significant difference in EQ VAS change between women in intervention (7,15 [95\% CI 4,32; 9,98]; EQ VAS t0: 75,35 [SD 13,71]) and control group (-2,63 [95\% CI -5,40; 0,15]; EQ VAS t0: 78,80 [SD 18,51]) from t0 to t1 was observed (p < 001; adjusted for baseline). No significant differences in mean EQ VAS change from t0 to t2 and in mean EQ-5D index change from t0 to t1 and t0 to t2 between the groups were observed (p > 0,05; adjusted for baseline). Conclusions The preliminary results suggest that the lifestyle intervention programme can have a positive short-time effect on some aspects of quality of life, such as the health profile and EQ VAS. However, the long-term results will be shown in the future. Key messages - A healthy lifestyle can affect the quality of life in a positive way. - The community-based lifestyle programme had a short-time influence on the descriptive health profile and EQ VAS of German women, whereby the EQ index didńt change significantly between the groups.}, language = {en} } @article{KoederHahnEnglert2021, author = {Koeder, Christian and Hahn, Andreas and Englert, Heike}, title = {Is fruit intake associated with common carotid intima-media thickness?}, series = {European Journal of Public Health}, journal = {European Journal of Public Health}, doi = {10.1093/eurpub/ckab165.391}, year = {2021}, abstract = {Background Common carotid intima-media thickness (ccIMT) is an established risk marker for cardiovascular events, including myocardial infarction and stroke, which are of high public health relevance. While a higher fruit intake is generally considered beneficial for cardiovascular health, recent studies have shown that a fruit intake of > 2 portions per day may be harmful. Therefore, we tested if there is an association between categories of fruit intake and mean ccIMT. Methods We conducted an exploratory, non-prespecified, cross-sectional analysis of baseline values of 167 mostly middle-aged participants of a controlled lifestyle intervention, recruited from the general population in rural northwest Germany (male: n = 58; female: n = 109). Fruit intake was classified into low (<1 portion of fruit/day), intermediate (1-2 portions of fruit/day), and high (>2 portions of fruit/day). Mean ccIMT was measured in accordance with the Mannheim consensus. Between-group differences in mean ccIMT were assessed with analysis of covariance. Results Mean age was 57.3 ± 0.7 years (mean ± SEM). Mean fruit intake was 1.6 ± 0.1 portions/day. Average mean ccIMT was 0.679 ± 0.010 mm. There was a significant difference in mean ccIMT between subjects with low (0.676 ± 0.020 mm; n = 50), intermediate (0.653 ± 0.014 mm; n = 72), and high fruit intake (0.724 ± 0.019 mm; n = 45; p = 0.016). But this difference was attenuated when adjusting for age, sex, and homocysteine (p = 0.418). Conclusions We found only a non-significant association between consuming >2 portions of fruit per day and ccIMT. Thus, our study could not confirm a negative effect of fruit intake on ccIMT. Age, sex, and homocysteine may confound this association. Key messages Current recommendations of 2 portions of fruit per day seem adequate and do not negatively influence carotid intima-media thickness. Future studies should address confounding of the association between fruit intake and cardiovascular risk markers.}, language = {en} } @article{KoederKranzAnandetal.2021, author = {Koeder, Christian and Kranz, Ragna-Marie and Anand, Corinna and Husain, Sarah and Alzughayyar, Dima and Schoch, Nora and Hahn, Andreas and Englert, Heike}, title = {Effect of a 1-year controlled lifestyle intervention on body weight and other risk markers (the Healthy Lifestyle Community Programme, cohort 2)}, series = {Obesity Facts}, journal = {Obesity Facts}, doi = {10.1159/000521164}, year = {2021}, language = {en} } @article{KentRankinMortonetal.2021, author = {Kent, Lillian and Rankin, Paul and Morton, Darren and Rankin, Rebekah and Greenlaw, Roger and Englert, Heike}, title = {Volunteers: An Effective Medium for Delivering Therapeutic Lifestyle Interventions}, series = {American Journal of Health Promotion}, journal = {American Journal of Health Promotion}, doi = {10.1177/08901171211062581}, year = {2021}, language = {en} } @article{KranzEnglert2020, author = {Kranz, Ragna-Marie and Englert, Heike}, title = {Entwicklung des Lebensstilprogramms „Gemeinsam Gesund"}, series = {Pr{\"a}vention und Gesundheitsf{\"o}rderung}, journal = {Pr{\"a}vention und Gesundheitsf{\"o}rderung}, doi = {10.1007/s11553-020-00759-z}, pages = {1 -- 7}, year = {2020}, abstract = {Zusammenfassung Hintergrund. Zivilisationserkrankungen (NCD) werden in Deutschland mit nahezu allen Sterbef{\"a}llen assoziiert. Durch einen gesunden Lebensstil l{\"a}sst sich das Erkran-kungsrisiko jedoch maßgeblich beeinflussen. Daraus leitet sich ein großes Potenzial f{\"u}r Lebensstilinterventionen zur Pr{\"a}vention und Gesundheitsf{\"o}rderung ab. Das community-basierte Lebensstilprogramm „Gemeinsam Gesund" kombiniert verhaltens- und verh{\"a}ltnispr{\"a}ventive Maßnahmen zur NCD-Pr{\"a}vention. Fragestellung. Wie l{\"a}sst sich das Programm „Gemeinsam Gesund" mithilfe des Interven-tion-Mapping-Ansatzes (IMA) entwickeln und strukturieren? Methodik. Die Planung des Lebensstil-programms erfolgte mithilfe des IMA. Die theoretische Planungsmethode erm{\"o}g-lichte eine in Teilschritte untergliederte Programmentwicklung, die von einer Analyse der Ausgangssituation und Zielfindung {\"u}ber die Maßnahmenfestlegung bis hin zur Evaluationsplanung reichte. Ergebnisse. Die Bedarfs- und Bestandsanalyse (Schritt I) konnte die Bedarfe und bereits eta-blierte Gesundheitsangebote der Community aufzeigen. Daraus konnten konkrete Ziele ent-wickelt (Schritt II) sowie Maßnahmenformate und -inhalte (Schritt III) festgelegt werden. Es wurden Gesundheitschecks und ein 10-w{\"o}chiges intensives Lebensstilprogramm mit anschließenden Alumni-Treffen konzipiert. F{\"u}r alle Interventionsinhalte wurden Materialien entwickelt (Schritt IV) und die Akteure f{\"u}r die Implementierung vor Ort identifiziert (Schritt V). F{\"u}r die Evaluation (Schritt VI) wurde eine Kombination aus einer Effekt- und Prozessevaluation geplant. Diskussion. Der IMA eignet sich gut zur Planung von komplexen Lebensstilprogram-men. Die Anwendung der Methode konnte zu einer sehr zielgruppenorientierten Inter-ventionsentwicklung beitragen, wenngleich einige Abweichungen von der normalen Vorgehensweise des IMA notwendig waren.}, language = {de} } @inproceedings{KranzEnglert2020, author = {Kranz, Ragna-Marie and Englert, Heike}, title = {Potenzial eines Community-basierten Lebensstilprogramms zur Pr{\"a}vention von Diabetes mellitus Typ 2 im gesundheits{\"o}konomischen Kontext}, series = {Proceedings of the German Nutrition Society}, booktitle = {Proceedings of the German Nutrition Society}, isbn = {978-3-88749-267-0}, pages = {73}, year = {2020}, abstract = {Hintergrund: Der globale Anstieg von lebensstilabhängigen Erkrankungen, wie Diabetes mellitus Typ 2 (DMT2), f{\"u}hrt zu enormen Belastungen f{\"u}r das Gesundheitssystem. Dabei er-weist sich insbesondere der DMT2 häufig durch regelmäßige Untersuchungen und Medikationen als sehr kostenintensiv. Vor diesem Hintergrund stellt sich die Frage, inwiefern ein Le-bensstilprogramm (LSP), durch die Senkung der N{\"u}chternglu-cose und des HbA1c-Wertes, das DM2T-Risikoprofil verbessern und dem {\"U}bergang des Prädiabetes in einen DMT2 entgegen-wirken sowie sukzessive Kosteneinsparungen erzielen kann.Methoden: Das LSP umfasst eine 24-monatige, prospektive und kontrollierte Interventionsstudie mit Personen ≥18Jah-ren. Datenerhebungen wurden zur Baseline (t0) sowie nach 10 Wochen (t1) und 6, 12, 18 und 24 Monaten (t2-t5) festge-legt. Dabei werden u.a. Laborparameter (z.B. N{\"u}chternglu-cose und HbA1c) sowie gesundheits{\"o}konomische Parameter (z.B. Behandlungen und Medikationen) erfasst. In der Inter-ventionsgruppe (N=112) wurden individuelle Coachings, ein 10-w{\"o}chiges intensives LSP und monatliche Folgetreffen durchgef{\"u}hrt. Die Kontrollgruppe (N=87) erhielt ein „Treat-ment as usual".Ergebnisse: In der Interventionsgruppe zeigte sich eine kon-tinuierliche Verringerung der N{\"u}chternglucose (p<0,05), bis-her jedoch keine signifikante HbA1c-Reduktion, innerhalb der ersten 3 Messzeitpunkte (t0-t2). In der Kontrollgruppe wurde eine geringere Senkung der N{\"u}chternglucose (p<0,01) sowie ein leichter Anstieg des HbA1c-Wertes (p<0,01) beobachtet (t0-t2).Schlussfolgerung: Das LSP konnte bisher zu einer Verbes-serung des DMT2-Risikoprofils f{\"u}hren (t0-t2) und kann sich präventiv auf die Manifestation und den {\"U}bergang eines Prä-diabetes in einen DMT2 auswirken. Daraus k{\"o}nnen Kosten-einsparungen abgeleitet werden. Die Auswertung weiterer Messzeitpunkte kann die langfristigen Auswirkungen des LSPs auf die Verbesserung von DMT2-assoziierten Parametern und damit verbundenen gesundheits{\"o}konomischen Parame-tern aufzeigen.}, language = {de} } @inproceedings{KoederEnglert2019, author = {K{\"o}der, Christian and Englert, Heike}, title = {Einfluss eines community-basierten Lebensstilinterventionsprogramms mit pflanzenbasierter Ern{\"a}hrung auf kardiovaskul{\"a}re Risikoparameter}, series = {Lebensjahre in Gesundheit - was leistet die Ern{\"a}hrung? Abstractband zum 56. Wissenschaftlichen Kongress}, booktitle = {Lebensjahre in Gesundheit - was leistet die Ern{\"a}hrung? Abstractband zum 56. Wissenschaftlichen Kongress}, editor = {Eckert, Gunter P. and Wenzel, Uwe}, publisher = {Deutsche Gesellschaft f{\"u}r Ern{\"a}hrung e. V. (DGE)}, address = {Bonn}, isbn = {978-3-88749-260-1}, pages = {85 -- 85}, year = {2019}, abstract = {Hintergrund: Kardiovaskul{\"a}re Erkrankungen (CVD) sind die f{\"u}hrende Todesursache in Deutschland und weltweit. Die Konzentrationen von Gesamtcholesterin und LDL-Cholesterin im Blut sind mit einem h{\"o}heren Risiko f{\"u}r CVD assoziiert. Die Intima-Media-Dicke der Arteria carotis communis (cIMT) erm{\"o}glicht es, den atherosklerotischen Prozess bereits im subklinischen Zustand und mittels einer schnell und einfach durchf{\"u}hrbaren, nichtinvasiven sowie f{\"u}r den Probanden gesundheitlich unbedenklichen Messung zu erfassen. Fragestellung: Ist das durchgef{\"u}hrte community-basierte Lebensstil-Interventionsprogramm geeignet, um das CVDRisiko zu senken? Methoden: Zweij{\"a}hrige kontrollierte Interventionsstudie mit 6 Messzeitpunkten (0, 2, 6, 12, 18, 24 Monate). F{\"u}r die Interventionsgruppe (N = 112) wurden ein individuelles Coaching sowie ein zehnw{\"o}chiges intensives Lebensstilprogramm mit anschließenden monatlichen Alumni-Treffen durchgef{\"u}hrt. Die Kontrollgruppe (N = 87) nimmt an keinem Programm teil. In beiden Gruppen werden u. a. die Parameter K{\"o}rpergewicht, Bauchumfang, Blutdruck, Puls, Blutzucker, HbA1c, Insulin, Cholesterinwerte, Triglyzeride, cIMT sowie Parameter zum Gesundheitsverhalten erfasst. Ergebnisse: In der Interventionsgruppe zeigte sich bisher nach 10 Wochen eine Verbesserung der Gesamtcholesterin- und LDL-Cholesterin- sowie der Blutzucker- und Insulinwerte. Das Risikoprofil in der Kontrollgruppe ver{\"a}nderte sich nicht. Die Bestimmung der cIMT ist nach nur 10 Wochen nicht sinnvoll. Ergebnisse zur cIMT werden erst nach 6 Monaten erneut erfasst und es liegen hierzu bisher nur die Baseline-Werte vor. Schlussfolgerung: Das durchgef{\"u}hrte Lebensstilprogramm ist geeignet, um das kardiovaskul{\"a}re Risikoprofil zu verbessern. Eine potenzielle Ver{\"a}nderung der cIMT muss langfristig beobachtet werden. Zuk{\"u}nftige Studien sollten in Bezug auf gesunde, pflanzenbasierte Lebensstile den Wissenstransfer in die Bev{\"o}lkerung hinein weiter optimieren.}, language = {de} } @inproceedings{KranzEnglert2019, author = {Kranz, Ragna-Marie and Englert, Heike}, title = {Potenzial eines community-basierten Lebensstilprogramms zur Verbesserung gesundheits{\"o}konomischer Parameter am Beispiel des LDL-Cholesterinspiegels und der Einnahme cholesterinsenkender Medikamente}, series = {Lebensjahre in Gesundheit - was leistet die Ern{\"a}hrung? Abstractband zum 56. Wissenschaftlichen Kongress}, booktitle = {Lebensjahre in Gesundheit - was leistet die Ern{\"a}hrung? Abstractband zum 56. Wissenschaftlichen Kongress}, publisher = {DGE}, address = {Bonn}, isbn = {978-3-88749-260-1}, pages = {51}, year = {2019}, abstract = {Potenzial eines community-basierten Lebensstilprogramms zur Verbesserung gesundheits{\"o}konomischer Parameter am Beispiel des LDL-Cholesterinspiegels und der Einnahme cholesterinsenkender Medikamente Hintergrund: Nicht-{\"u}bertragbare Zivilisationserkrankungen (NCDs) stellen eine enorme finanzielle Belastung f{\"u}r unser Gesundheitssystem dar. Erh{\"o}hte Lipidwerte, insbesondere der LDL-Cholesterinspiegel, gelten u. a. als Hauptrisikofaktoren f{\"u}r die Entstehung lebensstilabh{\"a}ngiger Erkrankungen und gehen nicht selten mit einer dauerhaften und kostenintensiven Medikation einher. Zahlreiche Studien konnten jedoch belegen, dass sich ein gesunder Lebensstil (gesunde Ern{\"a}hrung, Bewegung etc.) positiv auf den Verlauf kardiovaskul{\"a}rer Risikofaktoren auswirkt. Vor diesem Hintergrund besteht ein gesundheits politisch großes Interesse an der Implementierung von nachhaltigen Lebensstilinterventionen mit dem Ziel, langfristig eine Reduktion der Medikamenteneinnahme und konsekutiv eine Senkung der Gesundheitsausgaben zu erreichen. Methoden: Die kontrollierte Interventionsstudie umfasst 6 Messzeitpunkte {\"u}ber einen Zeitraum von 24 Monaten. F{\"u}r die Interventionsgruppe (n = 112) fanden individuelle Coachings und ein 10-w{\"o}chiges intensives Lebensstilprogramm mit anschließenden monatlichen Alumni-Treffen statt. Die Kontrollgruppe (n = 87) nahm an keinem Programm teil. In beiden Gruppen wurden, neben anthropometrischen, Vitalund Laborparametern (u. a. LDL-Cholesterin), gesundheits{\"o}konomische Parameter mithilfe von Frageb{\"o}gen erfasst. Ergebnisse: In der Interventionsgruppe zeigte sich bisher eine Verbesserung des LDL-Cholesterinspiegels nach 10 Wochen, wobei sich gleichzeitig eine Tendenz zu einer reduzierten Einnahme von cholesterinsenkenden Medikamenten abzeichnete. In der Kontrollgruppe wurden weder Ver{\"a}nderungen des LDLCholesterinspiegels noch Anpassungen der Medikamenteneinnahme beobachtet. Schlussfolgerung: Das community-basierte Lebens - stil programm eignet sich, um den LDL-Cholesterinspiegel im Blut zu senken und zeigt ein Potenzial zur verringerten Einnahme von cholesterinsenkenden Medikamenten auf. Zuk{\"u}nftig sollten die langfristigen Auswirkungen von Lebensstilinterventionen auf die Verbesserung des Lipid profils, die Reduktion der Medikamenteneinnahme sowie weitere gesundheits{\"o}konomische Parameter fokussiert werden.}, language = {de} } @inproceedings{TiggesEnglert2019, author = {Tigges, Corinna and Englert, Heike}, title = {Einfluss eines gemeinschaftsbasierten Lebensstil-Interventionsprogramms auf das kardiometabolische Risikoprofil erwachsener Menschen unter besonderer Ber{\"u}cksichtigung des subjektiv wahrgenommenen Stresslevels}, series = {Lebensjahre in Gesundheit - was leistet die Ern{\"a}hrung? Abstractband zum 56. Wissenschaftlichen DGE Kongress}, booktitle = {Lebensjahre in Gesundheit - was leistet die Ern{\"a}hrung? Abstractband zum 56. Wissenschaftlichen DGE Kongress}, editor = {Eckert, G{\"u}nter P and Wenzel, Uwe}, publisher = {Deutsche Gesellschaft f{\"u}r Ern{\"a}hrung e.V.}, address = {Bonn}, organization = {Deutsche Gesellschaft f{\"u}r Ern{\"a}hrung e.V.}, isbn = {978-3-88749-260-1}, pages = {26}, year = {2019}, abstract = {Hintergrund: Chronischen kardiometabolischen Krankheiten ist gemein, dass sie maßgeblich durch einen ungesunden Lebensstil (e.g. k{\"o}rperliche Inaktivit{\"a}t, hyperkalorische Ern{\"a}hrung mit ung{\"u}nstigen Verzehrsmustern, chronische Stresszust{\"a}nde) beg{\"u}nstigt werden. Vor diesem Hintergrund ist es von großem Interesse, Interventionen zu entwickeln, die die Implementierung eines gesundheitsf{\"o}rderlichen Lebensstils erm{\"o}glicht. Fragestellung: Ist ein gemeinschaftsbasiertes Interventionsprogramm zur F{\"o}rderung eines gesunden Lebensstils geeignet, das kardiometabolische Risikoprofil zu verbessern? Methoden: Die kontrollierte Interventionsstudie umfasst 6 Messzeitpunkte {\"u}ber den Zeitraum von insgesamt 24 Monaten. F{\"u}r die Interventionsgruppe (N = 107) fanden individuelle Gesundheitscoachings sowie ein zehnw{\"o}chiges intensives Lebensstilprogramm mit anschließenden monatlichen Alumni-Treffen statt. Die Kontrollgruppe (N = 45) erh{\"a}lt keine Behandlung. Neben anthropometrischen, Vital- und Laborparametern zur Bestimmung des metabolischen Risikoprofils wurde das subjektiv wahrgenommene Stresslevel (PSS-10) erfasst. Ergebnisse: Die Probanden der Interventionsgruppe zeigten eine Verbesserung des kardiovaskul{\"a}ren Risikoprofils nach 10 Wochen - w{\"a}hrend sich das Risikoprofil in der Kontrollgruppe nicht ver{\"a}nderte. Die Parameter n{\"a}herten sich auch in der Interventionsgruppe im weiteren Studienverlauf bis zum Messzeitpunkt t4 (nach 12 Monaten) wieder den Ausgangswerten an, erreichten das Ausgangniveau jedoch zumeist nicht. Schlussfolgerung: Das gemeinschaftsbasierte Lebensstilprogramm ist geeignet, um das kardiovaskul{\"a}re Risikoprofil erwachsener Menschen positiv zu beeinflussen. Zuk{\"u}nftig sollte der Fokus auf die nachhaltige Etablierung gesundheitsf{\"o}rderlicher Verhaltensweisen gelegt werden, um einen erneuten Anstieg des Risikos nach Beendigung der Intensivphase zu vermeiden.}, language = {de} }